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Mibefradil and Flunarizine, Two T-Type Calcium Channel Inhibitors, Protect Mice against Lipopolysaccharide-Induced Acute Lung Injury

Recent studies have illuminated that blocking Ca(2+) influx into effector cells is an attractive therapeutic strategy for lung injury. We hypothesize that T-type calcium channel may be a potential therapeutic target for acute lung injury (ALI). In this study, the pharmacological activity of mibefrad...

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Detalles Bibliográficos
Autores principales: Wan, Limei, Wu, Weibin, Jiang, Shunjun, Wan, Shanhe, Meng, Dongmei, Wang, Zhipeng, Zhang, Jiajie, Wei, Li, Yu, Pengjiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671802/
https://www.ncbi.nlm.nih.gov/pubmed/33223955
http://dx.doi.org/10.1155/2020/3691701