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Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development

Hematopoietic stem cells (HSCs) first emerge in the embryonic aorta-gonad-mesonephros (AGM) region. Studies of model organisms defined intersecting signaling pathways that converge to promote HSC emergence predominantly in the ventral domain of the dorsal aorta. Much less is known about mechanisms d...

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Detalles Bibliográficos
Autores principales:	Crosse, Edie I., Gordon-Keylock, Sabrina, Rybtsov, Stanislav, Binagui-Casas, Anahi, Felchle, Hannah, Nnadi, Nneka C., Kirschner, Kristina, Chandra, Tamir, Tamagno, Sara, Webb, David J., Rossi, Fiona, Anderson, Richard A., Medvinsky, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2020
Materias:	Resource
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671940/ https://www.ncbi.nlm.nih.gov/pubmed/32946788 http://dx.doi.org/10.1016/j.stem.2020.08.004

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