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Brain-Sparing Sympathofacilitators Mitigate Obesity without Adverse Cardiovascular Effects
Anti-obesity drugs in the amphetamine (AMPH) class act in the brain to reduce appetite and increase locomotion. They are also characterized by adverse cardiovascular effects with origin that, despite absence of any in vivo evidence, is attributed to a direct sympathomimetic action in the heart. Here...
Autores principales: | Mahú, Inês, Barateiro, Andreia, Rial-Pensado, Eva, Martinéz-Sánchez, Noelia, Vaz, Sandra H., Cal, Pedro M.S.D., Jenkins, Benjamin, Rodrigues, Tiago, Cordeiro, Carlos, Costa, Miguel F., Mendes, Raquel, Seixas, Elsa, Pereira, Mafalda M.A., Kubasova, Nadiya, Gres, Vitka, Morris, Imogen, Temporão, Carolina, Olivares, Marta, Sanz, Yolanda, Koulman, Albert, Corzana, Francisco, Sebastião, Ana M., López, Miguel, Bernardes, Gonçalo J.L., Domingos, Ana I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671941/ https://www.ncbi.nlm.nih.gov/pubmed/32402266 http://dx.doi.org/10.1016/j.cmet.2020.04.013 |
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