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Amyotrophic Lateral Sclerosis: Proteins, Proteostasis, Prions, and Promises

Amyotrophic lateral sclerosis (ALS) is characterized by the progressive degeneration of the motor neurons that innervate muscle, resulting in gradual paralysis and culminating in the inability to breathe or swallow. This neuronal degeneration occurs in a spatiotemporal manner from a point of onset i...

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Detalles Bibliográficos
Autores principales: McAlary, Luke, Chew, Yee Lian, Lum, Jeremy Stephen, Geraghty, Nicholas John, Yerbury, Justin John, Cashman, Neil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671971/
https://www.ncbi.nlm.nih.gov/pubmed/33328890
http://dx.doi.org/10.3389/fncel.2020.581907