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Synaptic mitochondrial dysfunction and septin accumulation are linked to complement-mediated synapse loss in an Alzheimer’s disease animal model

Synaptic functional disturbances with concomitant synapse loss represent central pathological hallmarks of Alzheimer’s disease. Excessive accumulation of cytotoxic amyloid oligomers is widely recognized as a key event that underlies neurodegeneration. Certain complement components are crucial instru...

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Detalles Bibliográficos
Autores principales:	Györffy, Balázs A., Tóth, Vilmos, Török, György, Gulyássy, Péter, Kovács, Réka Á., Vadászi, Henrietta, Micsonai, András, Tóth, Melinda E., Sántha, Miklós, Homolya, László, Drahos, László, Juhász, Gábor, Kékesi, Katalin A., Kardos, József
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671981/ https://www.ncbi.nlm.nih.gov/pubmed/32034429 http://dx.doi.org/10.1007/s00018-020-03468-0

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