Association Between Nitric Oxide, Oxidative Stress, Eryptosis, Red Blood Cell Microparticles, and Vascular Function in Sickle Cell Anemia

Chronic hemolysis, enhanced oxidative stress, and decreased nitric oxide (NO) bioavailability promote vasculopathy in sickle cell anemia (SCA). Oxidative stress and NO are known to modulate eryptosis in healthy red blood cells (RBCs); however, their role in SCA eryptosis and their impact on the gene...

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Detalles Bibliográficos
Autores principales: Nader, Elie, Romana, Marc, Guillot, Nicolas, Fort, Romain, Stauffer, Emeric, Lemonne, Nathalie, Garnier, Yohann, Skinner, Sarah Chambers, Etienne-Julan, Maryse, Robert, Mélanie, Gauthier, Alexandra, Cannas, Giovanna, Antoine-Jonville, Sophie, Tressières, Benoît, Hardy-Dessources, Marie-Dominique, Bertrand, Yves, Martin, Cyril, Renoux, Céline, Joly, Philippe, Grau, Marijke, Connes, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672038/
https://www.ncbi.nlm.nih.gov/pubmed/33250889
http://dx.doi.org/10.3389/fimmu.2020.551441

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