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Structure of the human sodium leak channel NALCN in complex with FAM155A
NALCN, a sodium leak channel expressed mainly in the central nervous system, is responsible for the resting Na(+) permeability that controls neuronal excitability. Dysfunctions of the NALCN channelosome, NALCN with several auxiliary subunits, are associated with a variety of human diseases. Here, we...
Autores principales: | Xie, Jiongfang, Ke, Meng, Xu, Lizhen, Lin, Shiyi, Huang, Jin, Zhang, Jiabei, Yang, Fan, Wu, Jianping, Yan, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672056/ https://www.ncbi.nlm.nih.gov/pubmed/33203861 http://dx.doi.org/10.1038/s41467-020-19667-z |
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