Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis

Systemic sclerosis (SSc) is a disease at the intersection of autoimmunity and fibrosis. However, the epigenetic regulation and the contributions of diverse cell types to SSc remain unclear. Here we survey, using ATAC-seq, the active DNA regulatory elements of eight types of primary cells in normal s...

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Detalles Bibliográficos
Autores principales: Liu, Qian, Zaba, Lisa, Satpathy, Ansuman T., Longmire, Michelle, Zhang, Wen, Li, Kun, Granja, Jeffrey, Guo, Chuang, Lin, Jun, Li, Rui, Tolentino, Karen, Kania, Gabriela, Distler, Oliver, Fiorentino, David, Chung, Lorinda, Qu, Kun, Chang, Howard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672105/
https://www.ncbi.nlm.nih.gov/pubmed/33203843
http://dx.doi.org/10.1038/s41467-020-19702-z

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