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Improved non-invasive positron emission tomographic imaging of chemotherapy-induced tumor cell death using Zirconium-89-labeled APOMAB®
PURPOSE: The chimeric monoclonal antibody (mAb) chDAB4 (APOMAB®) targets the Lupus associated (La)/Sjögren Syndrome-B (SSB) antigen, which is over-expressed in tumors but only becomes available for antibody binding in dead tumor cells. Hence, chDAB4 may be used as a novel theranostic tool to disting...
Autores principales: | Liapis, Vasilios, Tieu, William, Rudd, Stacey E., Donnelly, Paul S., Wittwer, Nicole L., Brown, Michael P., Staudacher, Alexander H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672150/ https://www.ncbi.nlm.nih.gov/pubmed/33205364 http://dx.doi.org/10.1186/s41181-020-00109-6 |
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