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Exploring the Link Between Additive Heritability and Prediction Accuracy From a Ridge Regression Perspective
Genome-Wide Association Studies (GWAS) explain only a small fraction of heritability for most complex human phenotypes. Genomic heritability estimates the variance explained by the SNPs on the whole genome using mixed models and accounts for the many small contributions of SNPs in the explanation of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672157/ https://www.ncbi.nlm.nih.gov/pubmed/33329721 http://dx.doi.org/10.3389/fgene.2020.581594 |