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Exploring the Link Between Additive Heritability and Prediction Accuracy From a Ridge Regression Perspective

Genome-Wide Association Studies (GWAS) explain only a small fraction of heritability for most complex human phenotypes. Genomic heritability estimates the variance explained by the SNPs on the whole genome using mixed models and accounts for the many small contributions of SNPs in the explanation of...

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Detalles Bibliográficos
Autores principales: Frouin, Arthur, Dandine-Roulland, Claire, Pierre-Jean, Morgane, Deleuze, Jean-François, Ambroise, Christophe, Le Floch, Edith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672157/
https://www.ncbi.nlm.nih.gov/pubmed/33329721
http://dx.doi.org/10.3389/fgene.2020.581594

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