Cargando…
Exploring the Link Between Additive Heritability and Prediction Accuracy From a Ridge Regression Perspective
Genome-Wide Association Studies (GWAS) explain only a small fraction of heritability for most complex human phenotypes. Genomic heritability estimates the variance explained by the SNPs on the whole genome using mixed models and accounts for the many small contributions of SNPs in the explanation of...
Autores principales: | Frouin, Arthur, Dandine-Roulland, Claire, Pierre-Jean, Morgane, Deleuze, Jean-François, Ambroise, Christophe, Le Floch, Edith |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672157/ https://www.ncbi.nlm.nih.gov/pubmed/33329721 http://dx.doi.org/10.3389/fgene.2020.581594 |
Ejemplares similares
-
Genome-wide haplotype association study in imaging genetics using whole-brain sulcal openings of 16,304 UK Biobank subjects
por: Karkar, Slim, et al.
Publicado: (2021) -
Accuracy of heritability estimations in presence of hidden population stratification
por: Dandine-Roulland, Claire, et al.
Publicado: (2016) -
Weak Association Between Genetic Markers of Hyperuricemia and Cardiorenal Outcomes: Insights From the STANISLAS Study Cohort With a 20‐Year Follow‐Up
por: Kanbay, Mehmet, et al.
Publicado: (2022) -
PCSK9 Protein and rs562556 Polymorphism Are Associated With Arterial Plaques in Healthy Middle‐Aged Population: The STANISLAS Cohort
por: Ferreira, João Pedro, et al.
Publicado: (2020) -
Impact of natriuretic peptide polymorphisms on diastolic and metabolic function in a populational cohort: insights from the STANISLAS cohort
por: Xhaard, Constance, et al.
Publicado: (2021)