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TruNeo: an integrated pipeline improves personalized true tumor neoantigen identification

BACKGROUND: Neoantigen-based personal vaccines and adoptive T cell immunotherapy have shown high efficacy as a cancer treatment in clinical trials. Algorithms for the accurate prediction of neoantigens have played a pivotal role in such studies. Some existing bioinformatics methods, such as MHCflurr...

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Detalles Bibliográficos
Autores principales: Tang, Yunxia, Wang, Yu, Wang, Jiaqian, Li, Miao, Peng, Linmin, Wei, Guochao, Zhang, Yixing, Li, Jin, Gao, Zhibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672179/
https://www.ncbi.nlm.nih.gov/pubmed/33208106
http://dx.doi.org/10.1186/s12859-020-03869-9

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