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Case Series: COVID-19 in African American Patients With Sarcoidosis

Data on the clinical presentation and outcomes of sarcoidosis patients with coronavirus disease 19 (COVID-19) are scarce. In this case series, we identified 5 out of 238 sarcoidosis patients who are enrolled in an ongoing longitudinal observational study who developed COVID-19 during the study perio...

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Autores principales: Manansala, Michael, Ascoli, Christian, Alburquerque, Ana Goico, Perkins, David, Mirsaedi, Mehdi, Finn, Patricia, Sweiss, Nadera J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672207/
https://www.ncbi.nlm.nih.gov/pubmed/33251236
http://dx.doi.org/10.3389/fmed.2020.588527
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author Manansala, Michael
Ascoli, Christian
Alburquerque, Ana Goico
Perkins, David
Mirsaedi, Mehdi
Finn, Patricia
Sweiss, Nadera J.
author_facet Manansala, Michael
Ascoli, Christian
Alburquerque, Ana Goico
Perkins, David
Mirsaedi, Mehdi
Finn, Patricia
Sweiss, Nadera J.
author_sort Manansala, Michael
collection PubMed
description Data on the clinical presentation and outcomes of sarcoidosis patients with coronavirus disease 19 (COVID-19) are scarce. In this case series, we identified 5 out of 238 sarcoidosis patients who are enrolled in an ongoing longitudinal observational study who developed COVID-19 during the study period and follow their clinical course. Four patients recovered completely, whereas one patient expired during hospital admission. Our preliminary experience suggests that African American patients with chronic sarcoidosis treated with disease-modifying anti-rheumatic drugs (DMARDs) or anti-tumor necrosis factor (TNF) therapy do not seem to be at increased risk of respiratory or life-threatening complications from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared with the general population, although at the present time, we advocate for maintaining a high level of vigilance and strict follow-up in this patient population.
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spelling pubmed-76722072020-11-26 Case Series: COVID-19 in African American Patients With Sarcoidosis Manansala, Michael Ascoli, Christian Alburquerque, Ana Goico Perkins, David Mirsaedi, Mehdi Finn, Patricia Sweiss, Nadera J. Front Med (Lausanne) Medicine Data on the clinical presentation and outcomes of sarcoidosis patients with coronavirus disease 19 (COVID-19) are scarce. In this case series, we identified 5 out of 238 sarcoidosis patients who are enrolled in an ongoing longitudinal observational study who developed COVID-19 during the study period and follow their clinical course. Four patients recovered completely, whereas one patient expired during hospital admission. Our preliminary experience suggests that African American patients with chronic sarcoidosis treated with disease-modifying anti-rheumatic drugs (DMARDs) or anti-tumor necrosis factor (TNF) therapy do not seem to be at increased risk of respiratory or life-threatening complications from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared with the general population, although at the present time, we advocate for maintaining a high level of vigilance and strict follow-up in this patient population. Frontiers Media S.A. 2020-11-04 /pmc/articles/PMC7672207/ /pubmed/33251236 http://dx.doi.org/10.3389/fmed.2020.588527 Text en Copyright © 2020 Manansala, Ascoli, Alburquerque, Perkins, Mirsaedi, Finn and Sweiss. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Manansala, Michael
Ascoli, Christian
Alburquerque, Ana Goico
Perkins, David
Mirsaedi, Mehdi
Finn, Patricia
Sweiss, Nadera J.
Case Series: COVID-19 in African American Patients With Sarcoidosis
title Case Series: COVID-19 in African American Patients With Sarcoidosis
title_full Case Series: COVID-19 in African American Patients With Sarcoidosis
title_fullStr Case Series: COVID-19 in African American Patients With Sarcoidosis
title_full_unstemmed Case Series: COVID-19 in African American Patients With Sarcoidosis
title_short Case Series: COVID-19 in African American Patients With Sarcoidosis
title_sort case series: covid-19 in african american patients with sarcoidosis
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672207/
https://www.ncbi.nlm.nih.gov/pubmed/33251236
http://dx.doi.org/10.3389/fmed.2020.588527
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