Cargando…
Case Series: COVID-19 in African American Patients With Sarcoidosis
Data on the clinical presentation and outcomes of sarcoidosis patients with coronavirus disease 19 (COVID-19) are scarce. In this case series, we identified 5 out of 238 sarcoidosis patients who are enrolled in an ongoing longitudinal observational study who developed COVID-19 during the study perio...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672207/ https://www.ncbi.nlm.nih.gov/pubmed/33251236 http://dx.doi.org/10.3389/fmed.2020.588527 |
_version_ | 1783611082794860544 |
---|---|
author | Manansala, Michael Ascoli, Christian Alburquerque, Ana Goico Perkins, David Mirsaedi, Mehdi Finn, Patricia Sweiss, Nadera J. |
author_facet | Manansala, Michael Ascoli, Christian Alburquerque, Ana Goico Perkins, David Mirsaedi, Mehdi Finn, Patricia Sweiss, Nadera J. |
author_sort | Manansala, Michael |
collection | PubMed |
description | Data on the clinical presentation and outcomes of sarcoidosis patients with coronavirus disease 19 (COVID-19) are scarce. In this case series, we identified 5 out of 238 sarcoidosis patients who are enrolled in an ongoing longitudinal observational study who developed COVID-19 during the study period and follow their clinical course. Four patients recovered completely, whereas one patient expired during hospital admission. Our preliminary experience suggests that African American patients with chronic sarcoidosis treated with disease-modifying anti-rheumatic drugs (DMARDs) or anti-tumor necrosis factor (TNF) therapy do not seem to be at increased risk of respiratory or life-threatening complications from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared with the general population, although at the present time, we advocate for maintaining a high level of vigilance and strict follow-up in this patient population. |
format | Online Article Text |
id | pubmed-7672207 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76722072020-11-26 Case Series: COVID-19 in African American Patients With Sarcoidosis Manansala, Michael Ascoli, Christian Alburquerque, Ana Goico Perkins, David Mirsaedi, Mehdi Finn, Patricia Sweiss, Nadera J. Front Med (Lausanne) Medicine Data on the clinical presentation and outcomes of sarcoidosis patients with coronavirus disease 19 (COVID-19) are scarce. In this case series, we identified 5 out of 238 sarcoidosis patients who are enrolled in an ongoing longitudinal observational study who developed COVID-19 during the study period and follow their clinical course. Four patients recovered completely, whereas one patient expired during hospital admission. Our preliminary experience suggests that African American patients with chronic sarcoidosis treated with disease-modifying anti-rheumatic drugs (DMARDs) or anti-tumor necrosis factor (TNF) therapy do not seem to be at increased risk of respiratory or life-threatening complications from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared with the general population, although at the present time, we advocate for maintaining a high level of vigilance and strict follow-up in this patient population. Frontiers Media S.A. 2020-11-04 /pmc/articles/PMC7672207/ /pubmed/33251236 http://dx.doi.org/10.3389/fmed.2020.588527 Text en Copyright © 2020 Manansala, Ascoli, Alburquerque, Perkins, Mirsaedi, Finn and Sweiss. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Manansala, Michael Ascoli, Christian Alburquerque, Ana Goico Perkins, David Mirsaedi, Mehdi Finn, Patricia Sweiss, Nadera J. Case Series: COVID-19 in African American Patients With Sarcoidosis |
title | Case Series: COVID-19 in African American Patients With Sarcoidosis |
title_full | Case Series: COVID-19 in African American Patients With Sarcoidosis |
title_fullStr | Case Series: COVID-19 in African American Patients With Sarcoidosis |
title_full_unstemmed | Case Series: COVID-19 in African American Patients With Sarcoidosis |
title_short | Case Series: COVID-19 in African American Patients With Sarcoidosis |
title_sort | case series: covid-19 in african american patients with sarcoidosis |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672207/ https://www.ncbi.nlm.nih.gov/pubmed/33251236 http://dx.doi.org/10.3389/fmed.2020.588527 |
work_keys_str_mv | AT manansalamichael caseseriescovid19inafricanamericanpatientswithsarcoidosis AT ascolichristian caseseriescovid19inafricanamericanpatientswithsarcoidosis AT alburquerqueanagoico caseseriescovid19inafricanamericanpatientswithsarcoidosis AT perkinsdavid caseseriescovid19inafricanamericanpatientswithsarcoidosis AT mirsaedimehdi caseseriescovid19inafricanamericanpatientswithsarcoidosis AT finnpatricia caseseriescovid19inafricanamericanpatientswithsarcoidosis AT sweissnaderaj caseseriescovid19inafricanamericanpatientswithsarcoidosis |