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Why do some asthma patients respond poorly to glucocorticoid therapy?
Glucocorticosteroids are the first-line therapy for controlling airway inflammation in asthma. They bind intracellular glucocorticoid receptors to trigger increased expression of anti-inflammatory genes and suppression of pro-inflammatory gene activation in asthmatic airways. In the majority of asth...
Autores principales: | Henderson, Ishbel, Caiazzo, Elisabetta, McSharry, Charles, Guzik, Tomasz J., Maffia, Pasquale |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672256/ https://www.ncbi.nlm.nih.gov/pubmed/32911071 http://dx.doi.org/10.1016/j.phrs.2020.105189 |
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