Cargando…

Anti-tumour effect of tocilizumab for osteosarcoma cell lines

AIMS: Tocilizumab, an interleukin-6 (IL-6) receptor (IL-6R) targeting antibody, enhances the anti-tumour effect of conventional chemotherapy in preclinical models of cancer. We investigated the anti-tumour effect of tocilizumab in osteosarcoma (OS) cell lines. METHODS: We used the 143B, HOS, and Sao...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hagi, Tomohito, Nakamura, Tomoki, Kita, Kouji, Iino, Takahiro, Asanuma, Kunihiro, Sudo, Akihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The British Editorial Society of Bone & Joint Surgery 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672325/ https://www.ncbi.nlm.nih.gov/pubmed/33179539 http://dx.doi.org/10.1302/2046-3758.911.BJR-2020-0123.R1

Ejemplares similares

Radiodynamic therapy with acridine orange local administration as a new treatment option for primary and secondary bone tumours
por: Matsuyama, Yumi, et al.
Publicado: (2022)

Expression of Interleukin-6 and the Interleukin-6 Receptor Predicts the Clinical Outcomes of Patients with Soft Tissue Sarcomas
por: Nakamura, Koichi, et al.
Publicado: (2020)

Soluble programmed death-ligand 1 rather than PD-L1 on tumor cells effectively predicts metastasis and prognosis in soft tissue sarcomas
por: Asanuma, Kunihiro, et al.
Publicado: (2020)

Macrophages and vimentin in tissues adjacent to megaprostheses and mesh in reconstructive surgeries
por: Asanuma, Kunihiro, et al.
Publicado: (2022)

Full-thickness chest wall resection for malignant chest wall tumors and postoperative problems
por: Asanuma, Kunihiro, et al.
Publicado: (2023)

A Novel Approach to Reducing Lung Metastasis in Osteosarcoma: Increasing Cell Stiffness with Carbenoxolone
por: Kita, Kouji, et al.
Publicado: (2023)

Cytoskeletal Actin Structure in Osteosarcoma Cells Determines Metastatic Phenotype via Regulating Cell Stiffness, Migration, and Transmigration
por: Kita, Kouji, et al.
Publicado: (2021)

Combination of Everolimus and Bortezomib Inhibits the Growth and Metastasis of Bone and Soft Tissue Sarcomas via JNK/p38/ERK MAPK and AKT Pathways
por: Nakamura, Koichi, et al.
Publicado: (2023)

The diagnostic and prognostic value of interleukin-6 in patients with soft tissue sarcomas
por: Hagi, Tomohito, et al.
Publicado: (2017)

The role of soluble CD80 in patients with soft tissue tumors
por: Matsuyama, Yumi, et al.
Publicado: (2022)

Successful treatment with cryoablation in a patient with bone metastasis in the mid-shaft femur: a case report
por: Kita, Kouji, et al.
Publicado: (2019)

Clinical Outcome of Systemic Treatment for Advanced Soft Tissue Sarcoma: Real-Life Perspective in Japan
por: Nakamura, Tomoki, et al.
Publicado: (2020)

Modified Glasgow Prognostic Score is Better for Predicting Oncological Outcome in Patients with Soft Tissue Sarcoma, Compared to High-Sensitivity Modified Glasgow Prognostic Score
por: Nakamura, Tomoki, et al.
Publicado: (2022)

Is Lymphocyte C-Reactive Protein Ratio Useful for Predicting Survival in Patients with Non-Metastatic Soft Tissue Sarcoma?
por: Nakamura, Tomoki, et al.
Publicado: (2022)

Significance of coagulation and fibrinolysis markers for benign and malignant soft tissue tumors
por: Asanuma, Kunihiro, et al.
Publicado: (2021)

Do coagulation or fibrinolysis reflect the disease condition in patients with soft tissue sarcoma?
por: Asanuma, Kunihiro, et al.
Publicado: (2022)

GPR64, Screened from Ewing Sarcoma Cells, Is a Potential Target for Antibody-Based Therapy for Various Sarcomas
por: Nakamura, Koichi, et al.
Publicado: (2022)

Prognostic Significance of Thrombomodulin mRNA in High‐Grade Soft Tissue Sarcomas after 10 years
por: Asanuma, Kunihiro, et al.
Publicado: (2020)

Thin Cartilage Cap May Be Related to the Spontaneous Regression in Pediatric Patients with Osteochondroma
por: Adachi, Ryohei, et al.
Publicado: (2022)

Carbonic anhydrase IX enhances tumor cell proliferation and tumor progression in osteosarcoma
por: Okuno, Kazuma, et al.
Publicado: (2018)

Infiltrative tumor growth patterns on magnetic resonance imaging associated with systemic inflammation and oncological outcome in patients with high-grade soft-tissue sarcoma
por: Nakamura, Tomoki, et al.
Publicado: (2017)

Gastric metastasis in patients with leiomyosarcoma: A case report
por: Uchiyama, Teruya, et al.
Publicado: (2023)

STAT3 inhibitor, cucurbitacin I, is a novel therapeutic agent for osteosarcoma
por: Oi, Toru, et al.
Publicado: (2016)

Spontaneous pneumothorax in a 17-year-old male patient with multiple exostoses: A case report and review of the literature
por: Nakamura, Koichi, et al.
Publicado: (2021)

The Feasibility of Using the Direct Anterior Approach for Total Hip Arthroplasty or Bipolar Hemiarthroplasty to Treat Femoral Neck Fractures among the Elderly
por: Ishiguro, Shigeo, et al.
Publicado: (2022)

New screw technique for posterior column and ischial fixation from the anterior approach for acetabular fractures
por: Asanuma, Kunihiro, et al.
Publicado: (2023)

Tocilizumab (monoclonal anti-IL-6R antibody) reverses anlotinib resistance in osteosarcoma
por: Xu, Jiuhui, et al.
Publicado: (2023)

Treatment of the benign bone tumors including femoral neck lesion using compression hip screw and synthetic bone graft
por: Nakamura, Tomoki, et al.
Publicado: (2015)

The clinical outcomes of total femur prosthesis in patients with musculoskeletal tumors
por: Kakimoto, Takuya, et al.
Publicado: (2019)

The adverse effect of an unplanned surgical excision of foot soft tissue sarcoma
por: Nishimura, Akinobu, et al.
Publicado: (2011)

Impact of tumor volume doubling time on post-metastatic survival in bone or soft-tissue sarcoma patients treated with metastasectomy and/or radiofrequency ablation of the lung
por: Nakamura, Tomoki, et al.
Publicado: (2017)

Extradural cryptococcoma at the sacral spine without bone involvement in an immunocompetent patient
por: Asanuma, Yumiko, et al.
Publicado: (2013)

Soluble Neural-cadherin as a novel biomarker for malignant bone and soft tissue tumors
por: Niimi, Rui, et al.
Publicado: (2013)

Analysis of pulmonary nodules in patients with high-grade soft tissue sarcomas
por: Nakamura, Tomoki, et al.
Publicado: (2017)

Immune response in adverse reactions to metal debris following metal-on-metal total hip arthroplasty
por: Hasegawa, Masahiro, et al.
Publicado: (2016)

A Case of Cementless Impaction Bone Graft in a Revision Total Hip Arthroplasty Requiring Calcar Reconstruction
por: Ishiguro, Shigeo, et al.
Publicado: (2021)

Protective Effect of Edaravone Against Oxidative Stress in C2C12 Myoblast and Impairment of Skeletal Muscle Regeneration Exposed to Ischemic Injury in Ob/ob Mice
por: Nakanishi, Takuya, et al.
Publicado: (2020)

Minimally invasive surgery using intraoperative electron-beam radiotherapy for the treatment of soft tissue sarcoma of the extremities with tendon involvement
por: Matsumine, Akihiko, et al.
Publicado: (2016)

Integrated analysis of anti-tumor roles of BAP1 in osteosarcoma
por: Hu, Dong, et al.
Publicado: (2022)

The Role of Trabectedin in Soft Tissue Sarcoma
por: Nakamura, Tomoki, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_201422m4svvltou06p5dnv1goa