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Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()()
Reactive perforating collagenosis is a rare perforating dermatosis clinically characterized by intensely pruritic hyperpigmented papules, plaques, and nodules with a central keratotic plug. Histopathology reveals transepidermal elimination of collagen fibers. Its pathophysiology is still under inves...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Dermatologia
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672397/ https://www.ncbi.nlm.nih.gov/pubmed/33036808 http://dx.doi.org/10.1016/j.abd.2020.03.015 |
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author | Hasbún, Catalina Sandoval, Mauricio González-Bombardiere, Sergio |
author_facet | Hasbún, Catalina Sandoval, Mauricio González-Bombardiere, Sergio |
author_sort | Hasbún, Catalina |
collection | PubMed |
description | Reactive perforating collagenosis is a rare perforating dermatosis clinically characterized by intensely pruritic hyperpigmented papules, plaques, and nodules with a central keratotic plug. Histopathology reveals transepidermal elimination of collagen fibers. Its pathophysiology is still under investigation, but the acquired form has been linked to systemic conditions such as diabetes mellitus and chronic kidney disease. However, it has also been described as a paraneoplastic syndrome. The authors present the case of a 65-year-old diabetic patient in which a myeloproliferative neoplasm was suspected. |
format | Online Article Text |
id | pubmed-7672397 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-76723972020-11-24 Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()() Hasbún, Catalina Sandoval, Mauricio González-Bombardiere, Sergio An Bras Dermatol What Is Your Diagnosis? Reactive perforating collagenosis is a rare perforating dermatosis clinically characterized by intensely pruritic hyperpigmented papules, plaques, and nodules with a central keratotic plug. Histopathology reveals transepidermal elimination of collagen fibers. Its pathophysiology is still under investigation, but the acquired form has been linked to systemic conditions such as diabetes mellitus and chronic kidney disease. However, it has also been described as a paraneoplastic syndrome. The authors present the case of a 65-year-old diabetic patient in which a myeloproliferative neoplasm was suspected. Sociedade Brasileira de Dermatologia 2020 2020-09-13 /pmc/articles/PMC7672397/ /pubmed/33036808 http://dx.doi.org/10.1016/j.abd.2020.03.015 Text en © 2020 Published by Elsevier España, S.L.U. on behalf of Sociedade Brasileira de Dermatologia. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | What Is Your Diagnosis? Hasbún, Catalina Sandoval, Mauricio González-Bombardiere, Sergio Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()() |
title | Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()() |
title_full | Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()() |
title_fullStr | Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()() |
title_full_unstemmed | Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()() |
title_short | Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()() |
title_sort | case for diagnosis. hyperpigmented and excoriated papules and nodules in a diabetic patient()() |
topic | What Is Your Diagnosis? |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672397/ https://www.ncbi.nlm.nih.gov/pubmed/33036808 http://dx.doi.org/10.1016/j.abd.2020.03.015 |
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