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Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()()

Reactive perforating collagenosis is a rare perforating dermatosis clinically characterized by intensely pruritic hyperpigmented papules, plaques, and nodules with a central keratotic plug. Histopathology reveals transepidermal elimination of collagen fibers. Its pathophysiology is still under inves...

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Autores principales: Hasbún, Catalina, Sandoval, Mauricio, González-Bombardiere, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672397/
https://www.ncbi.nlm.nih.gov/pubmed/33036808
http://dx.doi.org/10.1016/j.abd.2020.03.015
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author Hasbún, Catalina
Sandoval, Mauricio
González-Bombardiere, Sergio
author_facet Hasbún, Catalina
Sandoval, Mauricio
González-Bombardiere, Sergio
author_sort Hasbún, Catalina
collection PubMed
description Reactive perforating collagenosis is a rare perforating dermatosis clinically characterized by intensely pruritic hyperpigmented papules, plaques, and nodules with a central keratotic plug. Histopathology reveals transepidermal elimination of collagen fibers. Its pathophysiology is still under investigation, but the acquired form has been linked to systemic conditions such as diabetes mellitus and chronic kidney disease. However, it has also been described as a paraneoplastic syndrome. The authors present the case of a 65-year-old diabetic patient in which a myeloproliferative neoplasm was suspected.
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spelling pubmed-76723972020-11-24 Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()() Hasbún, Catalina Sandoval, Mauricio González-Bombardiere, Sergio An Bras Dermatol What Is Your Diagnosis? Reactive perforating collagenosis is a rare perforating dermatosis clinically characterized by intensely pruritic hyperpigmented papules, plaques, and nodules with a central keratotic plug. Histopathology reveals transepidermal elimination of collagen fibers. Its pathophysiology is still under investigation, but the acquired form has been linked to systemic conditions such as diabetes mellitus and chronic kidney disease. However, it has also been described as a paraneoplastic syndrome. The authors present the case of a 65-year-old diabetic patient in which a myeloproliferative neoplasm was suspected. Sociedade Brasileira de Dermatologia 2020 2020-09-13 /pmc/articles/PMC7672397/ /pubmed/33036808 http://dx.doi.org/10.1016/j.abd.2020.03.015 Text en © 2020 Published by Elsevier España, S.L.U. on behalf of Sociedade Brasileira de Dermatologia. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle What Is Your Diagnosis?
Hasbún, Catalina
Sandoval, Mauricio
González-Bombardiere, Sergio
Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()()
title Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()()
title_full Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()()
title_fullStr Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()()
title_full_unstemmed Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()()
title_short Case for diagnosis. Hyperpigmented and excoriated papules and nodules in a diabetic patient()()
title_sort case for diagnosis. hyperpigmented and excoriated papules and nodules in a diabetic patient()()
topic What Is Your Diagnosis?
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672397/
https://www.ncbi.nlm.nih.gov/pubmed/33036808
http://dx.doi.org/10.1016/j.abd.2020.03.015
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