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Efficient DNA double-strand break formation at single or multiple defined sites in the Saccharomyces cerevisiae genome

DNA double-strand breaks (DSBs) are common genome lesions that threaten genome stability and cell survival. Cells use sophisticated repair machineries to detect and heal DSBs. To study DSB repair pathways and associated factors, inducible site-specific endonucleases have proven to be fundamental too...

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Detalles Bibliográficos
Autores principales:	Gnügge, Robert, Symington, Lorraine S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672422/ https://www.ncbi.nlm.nih.gov/pubmed/33053188 http://dx.doi.org/10.1093/nar/gkaa833

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