DNA and RNA editing without sequence limitation using the flap endonuclease 1 guided by hairpin DNA probes

Here, we characterized a flap endonuclease 1 (FEN1) plus hairpin DNA probe (hpDNA) system, designated the HpSGN system, for both DNA and RNA editing without sequence limitation. The compact size of the HpSGN system make it an ideal candidate for in vivo delivery applications. In vitro biochemical st...

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Detalles Bibliográficos
Autores principales: Tian, Kun, Guo, Yongjian, Zou, Bingjie, Wang, Liang, Zhang, Yun, Qi, Zhen, Zhou, Jieying, Wang, Xiaotang, Zhou, Guohua, Wei, Libin, Xu, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672438/
https://www.ncbi.nlm.nih.gov/pubmed/33051689
http://dx.doi.org/10.1093/nar/gkaa843

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