Structural basis of the XPB helicase–Bax1 nuclease complex interacting with the repair bubble DNA

Nucleotide excision repair (NER) removes various DNA lesions caused by UV light and chemical carcinogens. The DNA helicase XPB plays a key role in DNA opening and coordinating damage incision by nucleases during NER, but the underlying mechanisms remain unclear. Here, we report crystal structures of...

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Detalles Bibliográficos
Autores principales: He, Feng, DuPrez, Kevin, Hilario, Eduardo, Chen, Zhenhang, Fan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672443/
https://www.ncbi.nlm.nih.gov/pubmed/32986831
http://dx.doi.org/10.1093/nar/gkaa801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672443/
https://www.ncbi.nlm.nih.gov/pubmed/32986831
http://dx.doi.org/10.1093/nar/gkaa801

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