Cargando…
Structural basis of the XPB helicase–Bax1 nuclease complex interacting with the repair bubble DNA
Nucleotide excision repair (NER) removes various DNA lesions caused by UV light and chemical carcinogens. The DNA helicase XPB plays a key role in DNA opening and coordinating damage incision by nucleases during NER, but the underlying mechanisms remain unclear. Here, we report crystal structures of...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672443/ https://www.ncbi.nlm.nih.gov/pubmed/32986831 http://dx.doi.org/10.1093/nar/gkaa801 |