Synthetic rewiring and boosting type I interferon responses for visualization and counteracting viral infections

Mammalian first line of defense against viruses is accomplished by the interferon (IFN) system. Viruses have evolved numerous mechanisms to reduce the IFN action allowing them to invade the host and/or to establish latency. We generated an IFN responsive intracellular hub by integrating the syntheti...

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Detalles Bibliográficos
Autores principales: Gödecke, Natascha, Riedel, Jan, Herrmann, Sabrina, Behme, Sara, Rand, Ulfert, Kubsch, Tobias, Cicin-Sain, Luka, Hauser, Hansjörg, Köster, Mario, Wirth, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672444/
https://www.ncbi.nlm.nih.gov/pubmed/33137201
http://dx.doi.org/10.1093/nar/gkaa961

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