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A combinatorial method to isolate short ribozymes from complex ribozyme libraries
In vitro selections are the only known methods to generate catalytic RNAs (ribozymes) that do not exist in nature. Such new ribozymes are used as biochemical tools, or to address questions on early stages of life. In both cases, it is helpful to identify the shortest possible ribozymes since they ar...
Autores principales: | Arriola, Joshua T, Müller, Ulrich F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672470/ https://www.ncbi.nlm.nih.gov/pubmed/33035338 http://dx.doi.org/10.1093/nar/gkaa834 |
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