Label-free profiling of DNA aptamer-small molecule binding using T5 exonuclease

In vitro aptamer isolation methods can yield hundreds of potential candidates, but selecting the optimal aptamer for a given application is challenging and laborious. Existing aptamer characterization methods either entail low-throughput analysis with sophisticated instrumentation, or offer the pote...

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Detalles Bibliográficos
Autores principales: Alkhamis, Obtin, Yang, Weijuan, Farhana, Rifat, Yu, Haixiang, Xiao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672472/
https://www.ncbi.nlm.nih.gov/pubmed/33053182
http://dx.doi.org/10.1093/nar/gkaa849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672472/
https://www.ncbi.nlm.nih.gov/pubmed/33053182
http://dx.doi.org/10.1093/nar/gkaa849

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