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Label-free profiling of DNA aptamer-small molecule binding using T5 exonuclease
In vitro aptamer isolation methods can yield hundreds of potential candidates, but selecting the optimal aptamer for a given application is challenging and laborious. Existing aptamer characterization methods either entail low-throughput analysis with sophisticated instrumentation, or offer the pote...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672472/ https://www.ncbi.nlm.nih.gov/pubmed/33053182 http://dx.doi.org/10.1093/nar/gkaa849 |