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Hypoxia Regulates DPP4 Expression, Proteolytic Inactivation, and Shedding from Ovarian Cancer Cells

The treatment of ovarian cancer has not significantly changed in decades and it remains one of the most lethal malignancies in women. The serine protease dipeptidyl peptidase 4 (DPP4) plays key roles in metabolism and immunity, and its expression has been associated with either pro- or anti-tumour e...

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Detalles Bibliográficos
Autores principales: Moffitt, Laura R., Bilandzic, Maree, Wilson, Amy L., Chen, Yiqian, Gorrell, Mark D., Oehler, Martin K., Plebanski, Magdalena, Stephens, Andrew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672561/
https://www.ncbi.nlm.nih.gov/pubmed/33143089
http://dx.doi.org/10.3390/ijms21218110