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Inhibiting P2Y12 in Macrophages Induces Endoplasmic Reticulum Stress and Promotes an Anti-Tumoral Phenotype

The P2Y12 receptor is an adenosine diphosphate responsive G protein-coupled receptor expressed on the surface of platelets and is the pharmacologic target of several anti-thrombotic agents. In this study, we use liver samples from mice with cirrhosis and hepatocellular carcinoma to show that P2Y12 i...

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Detalles Bibliográficos
Autores principales:	Pavlović, Nataša, Kopsida, Maria, Gerwins, Pär, Heindryckx, Femke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672568/ https://www.ncbi.nlm.nih.gov/pubmed/33142937 http://dx.doi.org/10.3390/ijms21218177

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