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Yeast Rpn4 Links the Proteasome and DNA Repair via RAD52 Regulation

Environmental and intracellular factors often damage DNA, but multiple DNA repair pathways maintain genome integrity. In yeast, the 26S proteasome and its transcriptional regulator and substrate Rpn4 are involved in DNA damage resistance. Paradoxically, while proteasome dysfunction may induce hyper-...

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Detalles Bibliográficos
Autores principales: Spasskaya, Daria S., Nadolinskaia, Nonna I., Tutyaeva, Vera V., Lysov, Yuriy P., Karpov, Vadim L., Karpov, Dmitry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672625/
https://www.ncbi.nlm.nih.gov/pubmed/33143019
http://dx.doi.org/10.3390/ijms21218097