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Yeast Rpn4 Links the Proteasome and DNA Repair via RAD52 Regulation
Environmental and intracellular factors often damage DNA, but multiple DNA repair pathways maintain genome integrity. In yeast, the 26S proteasome and its transcriptional regulator and substrate Rpn4 are involved in DNA damage resistance. Paradoxically, while proteasome dysfunction may induce hyper-...
Autores principales: | Spasskaya, Daria S., Nadolinskaia, Nonna I., Tutyaeva, Vera V., Lysov, Yuriy P., Karpov, Vadim L., Karpov, Dmitry S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672625/ https://www.ncbi.nlm.nih.gov/pubmed/33143019 http://dx.doi.org/10.3390/ijms21218097 |
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