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Fc-optimized antibodies elicit CD8 immunity to viral respiratory infection

Antibodies against viral pathogens represent promising therapeutic agents for the control of infection, and their antiviral efficacy has been shown to require the coordinated function of both the Fab and Fc domains(1). The Fc domain engages a wide spectrum of receptors on discrete cells of the immun...

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Detalles Bibliográficos
Autores principales: Bournazos, Stylianos, Corti, Davide, Virgin, Herbert W., Ravetch, Jeffrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672690/
https://www.ncbi.nlm.nih.gov/pubmed/33032297
http://dx.doi.org/10.1038/s41586-020-2838-z

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