Cargando…
Fc-optimized antibodies elicit CD8 immunity to viral respiratory infection
Antibodies against viral pathogens represent promising therapeutic agents for the control of infection, and their antiviral efficacy has been shown to require the coordinated function of both the Fab and Fc domains(1). The Fc domain engages a wide spectrum of receptors on discrete cells of the immun...
Autores principales: | Bournazos, Stylianos, Corti, Davide, Virgin, Herbert W., Ravetch, Jeffrey V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672690/ https://www.ncbi.nlm.nih.gov/pubmed/33032297 http://dx.doi.org/10.1038/s41586-020-2838-z |
Ejemplares similares
-
The role of IgG Fc receptors in antibody-dependent enhancement
por: Bournazos, Stylianos, et al.
Publicado: (2020) -
The role of Fc–FcγR interactions in IgG-mediated microbial neutralization
por: Bournazos, Stylianos, et al.
Publicado: (2015) -
A novel mouse strain optimized for chronic human antibody administration
por: Gupta, Aaron, et al.
Publicado: (2022) -
A new mouse expressing human Fcγ receptors to better predict therapeutic efficacy of human anti-cancer antibodies
por: Casey, Emily, et al.
Publicado: (2017) -
Fc-engineered antibody therapeutics with improved efficacy against COVID-19
por: Yamin, Rachel, et al.
Publicado: (2021)