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Effects of macitentan and tadalafil monotherapy or their combination on the right ventricle and plasma metabolites in pulmonary hypertensive rats

Pulmonary arterial hypertension is a severe respiratory disease characterized by pulmonary artery remodeling. RV dysfunction and dysregulated circulating metabolomics are associated with adverse outcomes in pulmonary arterial hypertension. We investigated effects of tadalafil and macitentan alone or...

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Detalles Bibliográficos
Autores principales:	Mamazhakypov, Argen, Weiß, Astrid, Zukunft, Sven, Sydykov, Akylbek, Kojonazarov, Baktybek, Wilhelm, Jochen, Vroom, Christina, Petrovic, Aleksandar, Kosanovic, Djuro, Weissmann, Norbert, Seeger, Werner, Fleming, Ingrid, Iglarz, Marc, Grimminger, Friedrich, Ghofrani, Hossein A., Pullamsetti, Soni S., Schermuly, Ralph T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672745/ https://www.ncbi.nlm.nih.gov/pubmed/33240483 http://dx.doi.org/10.1177/2045894020947283

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