The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties

INTRODUCTION: In this study, we aimed to investigate the relationship between coronary slow flow (CSF) and carotid-femoral pulse wave velocity (CFPWV). METHODS: 78 (27 women, mean age 43.95 ± 7.28) patients with CSF, and 70 (22 women, mean age 44.34 ± 7.08) healthy individuals were included in the s...

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Autores principales: Akkaya, Hasan, Güntürk, Ertuğrul Emre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672767/
https://www.ncbi.nlm.nih.gov/pubmed/33240493
http://dx.doi.org/10.1177/2048004020973094
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author Akkaya, Hasan
Güntürk, Ertuğrul Emre
author_facet Akkaya, Hasan
Güntürk, Ertuğrul Emre
author_sort Akkaya, Hasan
collection PubMed
description INTRODUCTION: In this study, we aimed to investigate the relationship between coronary slow flow (CSF) and carotid-femoral pulse wave velocity (CFPWV). METHODS: 78 (27 women, mean age 43.95 ± 7.28) patients with CSF, and 70 (22 women, mean age 44.34 ± 7.08) healthy individuals were included in the study. Arterial stiffness measurement was performed to both groups via CFPWV, which is considered the gold standard. Aortic elastic properties (ASI-β and aortic distensibility) were evaluated in both groups. RESULTS: The CSF group had significantly higher CFPWV and aortic distensibility values and significantly lower ASI-β values compared to the control group. There was a positive correlation between TIMI frame count (TFC) obtained in all coronary arteries and CFPWV and aortic distensibility, and a negative correlation between TFC and ASI-β. It was determined that CFPWV predicted CSF with 97% specificity and 98% sensitivity at a 7.68 cut-off value (ROC area = 994, p < 0.001). ASI-β was determined to predict CSF with 64% specificity and 47% sensitivity at a 2.98 cut-off value (ROC area = 047, p < 0.001). Aortic distensibility was determined to predict CSF with 76% specificity and 79% sensitivity at a 3.94 cut-off value (ROC area = 706, p < 0.001). CONCLUSION: Arterial stiffness increases in CSF patients, suggesting that CSF is a systemic pathology rather than a local disease and that a systemic cause such as atherosclerosis plays a role in etiology.
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spelling pubmed-76727672020-11-24 The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties Akkaya, Hasan Güntürk, Ertuğrul Emre JRSM Cardiovasc Dis Research Paper INTRODUCTION: In this study, we aimed to investigate the relationship between coronary slow flow (CSF) and carotid-femoral pulse wave velocity (CFPWV). METHODS: 78 (27 women, mean age 43.95 ± 7.28) patients with CSF, and 70 (22 women, mean age 44.34 ± 7.08) healthy individuals were included in the study. Arterial stiffness measurement was performed to both groups via CFPWV, which is considered the gold standard. Aortic elastic properties (ASI-β and aortic distensibility) were evaluated in both groups. RESULTS: The CSF group had significantly higher CFPWV and aortic distensibility values and significantly lower ASI-β values compared to the control group. There was a positive correlation between TIMI frame count (TFC) obtained in all coronary arteries and CFPWV and aortic distensibility, and a negative correlation between TFC and ASI-β. It was determined that CFPWV predicted CSF with 97% specificity and 98% sensitivity at a 7.68 cut-off value (ROC area = 994, p < 0.001). ASI-β was determined to predict CSF with 64% specificity and 47% sensitivity at a 2.98 cut-off value (ROC area = 047, p < 0.001). Aortic distensibility was determined to predict CSF with 76% specificity and 79% sensitivity at a 3.94 cut-off value (ROC area = 706, p < 0.001). CONCLUSION: Arterial stiffness increases in CSF patients, suggesting that CSF is a systemic pathology rather than a local disease and that a systemic cause such as atherosclerosis plays a role in etiology. SAGE Publications 2020-11-11 /pmc/articles/PMC7672767/ /pubmed/33240493 http://dx.doi.org/10.1177/2048004020973094 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Research Paper
Akkaya, Hasan
Güntürk, Ertuğrul Emre
The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties
title The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties
title_full The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties
title_fullStr The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties
title_full_unstemmed The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties
title_short The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties
title_sort relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672767/
https://www.ncbi.nlm.nih.gov/pubmed/33240493
http://dx.doi.org/10.1177/2048004020973094
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