The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties
INTRODUCTION: In this study, we aimed to investigate the relationship between coronary slow flow (CSF) and carotid-femoral pulse wave velocity (CFPWV). METHODS: 78 (27 women, mean age 43.95 ± 7.28) patients with CSF, and 70 (22 women, mean age 44.34 ± 7.08) healthy individuals were included in the s...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672767/ https://www.ncbi.nlm.nih.gov/pubmed/33240493 http://dx.doi.org/10.1177/2048004020973094 |
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author | Akkaya, Hasan Güntürk, Ertuğrul Emre |
author_facet | Akkaya, Hasan Güntürk, Ertuğrul Emre |
author_sort | Akkaya, Hasan |
collection | PubMed |
description | INTRODUCTION: In this study, we aimed to investigate the relationship between coronary slow flow (CSF) and carotid-femoral pulse wave velocity (CFPWV). METHODS: 78 (27 women, mean age 43.95 ± 7.28) patients with CSF, and 70 (22 women, mean age 44.34 ± 7.08) healthy individuals were included in the study. Arterial stiffness measurement was performed to both groups via CFPWV, which is considered the gold standard. Aortic elastic properties (ASI-β and aortic distensibility) were evaluated in both groups. RESULTS: The CSF group had significantly higher CFPWV and aortic distensibility values and significantly lower ASI-β values compared to the control group. There was a positive correlation between TIMI frame count (TFC) obtained in all coronary arteries and CFPWV and aortic distensibility, and a negative correlation between TFC and ASI-β. It was determined that CFPWV predicted CSF with 97% specificity and 98% sensitivity at a 7.68 cut-off value (ROC area = 994, p < 0.001). ASI-β was determined to predict CSF with 64% specificity and 47% sensitivity at a 2.98 cut-off value (ROC area = 047, p < 0.001). Aortic distensibility was determined to predict CSF with 76% specificity and 79% sensitivity at a 3.94 cut-off value (ROC area = 706, p < 0.001). CONCLUSION: Arterial stiffness increases in CSF patients, suggesting that CSF is a systemic pathology rather than a local disease and that a systemic cause such as atherosclerosis plays a role in etiology. |
format | Online Article Text |
id | pubmed-7672767 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-76727672020-11-24 The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties Akkaya, Hasan Güntürk, Ertuğrul Emre JRSM Cardiovasc Dis Research Paper INTRODUCTION: In this study, we aimed to investigate the relationship between coronary slow flow (CSF) and carotid-femoral pulse wave velocity (CFPWV). METHODS: 78 (27 women, mean age 43.95 ± 7.28) patients with CSF, and 70 (22 women, mean age 44.34 ± 7.08) healthy individuals were included in the study. Arterial stiffness measurement was performed to both groups via CFPWV, which is considered the gold standard. Aortic elastic properties (ASI-β and aortic distensibility) were evaluated in both groups. RESULTS: The CSF group had significantly higher CFPWV and aortic distensibility values and significantly lower ASI-β values compared to the control group. There was a positive correlation between TIMI frame count (TFC) obtained in all coronary arteries and CFPWV and aortic distensibility, and a negative correlation between TFC and ASI-β. It was determined that CFPWV predicted CSF with 97% specificity and 98% sensitivity at a 7.68 cut-off value (ROC area = 994, p < 0.001). ASI-β was determined to predict CSF with 64% specificity and 47% sensitivity at a 2.98 cut-off value (ROC area = 047, p < 0.001). Aortic distensibility was determined to predict CSF with 76% specificity and 79% sensitivity at a 3.94 cut-off value (ROC area = 706, p < 0.001). CONCLUSION: Arterial stiffness increases in CSF patients, suggesting that CSF is a systemic pathology rather than a local disease and that a systemic cause such as atherosclerosis plays a role in etiology. SAGE Publications 2020-11-11 /pmc/articles/PMC7672767/ /pubmed/33240493 http://dx.doi.org/10.1177/2048004020973094 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Research Paper Akkaya, Hasan Güntürk, Ertuğrul Emre The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties |
title | The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties |
title_full | The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties |
title_fullStr | The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties |
title_full_unstemmed | The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties |
title_short | The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties |
title_sort | relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties |
topic | Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672767/ https://www.ncbi.nlm.nih.gov/pubmed/33240493 http://dx.doi.org/10.1177/2048004020973094 |
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