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A multi-label classification model for full slice brain computerised tomography image

BACKGROUND: Screening of the brain computerised tomography (CT) images is a primary method currently used for initial detection of patients with brain trauma or other conditions. In recent years, deep learning technique has shown remarkable advantages in the clinical practice. Researchers have attem...

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Autores principales: Li, Jianqiang, Fu, Guanghui, Chen, Yueda, Li, Pengzhi, Liu, Bo, Pei, Yan, Feng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672970/
https://www.ncbi.nlm.nih.gov/pubmed/33203366
http://dx.doi.org/10.1186/s12859-020-3503-0
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author Li, Jianqiang
Fu, Guanghui
Chen, Yueda
Li, Pengzhi
Liu, Bo
Pei, Yan
Feng, Hui
author_facet Li, Jianqiang
Fu, Guanghui
Chen, Yueda
Li, Pengzhi
Liu, Bo
Pei, Yan
Feng, Hui
author_sort Li, Jianqiang
collection PubMed
description BACKGROUND: Screening of the brain computerised tomography (CT) images is a primary method currently used for initial detection of patients with brain trauma or other conditions. In recent years, deep learning technique has shown remarkable advantages in the clinical practice. Researchers have attempted to use deep learning methods to detect brain diseases from CT images. Methods often used to detect diseases choose images with visible lesions from full-slice brain CT scans, which need to be labelled by doctors. This is an inaccurate method because doctors detect brain disease from a full sequence scan of CT images and one patient may have multiple concurrent conditions in practice. The method cannot take into account the dependencies between the slices and the causal relationships among various brain diseases. Moreover, labelling images slice by slice spends much time and expense. Detecting multiple diseases from full slice brain CT images is, therefore, an important research subject with practical implications. RESULTS: In this paper, we propose a model called the slice dependencies learning model (SDLM). It learns image features from a series of variable length brain CT images and slice dependencies between different slices in a set of images to predict abnormalities. The model is necessary to only label the disease reflected in the full-slice brain scan. We use the CQ500 dataset to evaluate our proposed model, which contains 1194 full sets of CT scans from a total of 491 subjects. Each set of data from one subject contains scans with one to eight different slice thicknesses and various diseases that are captured in a range of 30 to 396 slices in a set. The evaluation results present that the precision is 67.57%, the recall is 61.04%, the F1 score is 0.6412, and the areas under the receiver operating characteristic curves (AUCs) is 0.8934. CONCLUSION: The proposed model is a new architecture that uses a full-slice brain CT scan for multi-label classification, unlike the traditional methods which only classify the brain images at the slice level. It has great potential for application to multi-label detection problems, especially with regard to the brain CT images.
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spelling pubmed-76729702020-11-20 A multi-label classification model for full slice brain computerised tomography image Li, Jianqiang Fu, Guanghui Chen, Yueda Li, Pengzhi Liu, Bo Pei, Yan Feng, Hui BMC Bioinformatics Research BACKGROUND: Screening of the brain computerised tomography (CT) images is a primary method currently used for initial detection of patients with brain trauma or other conditions. In recent years, deep learning technique has shown remarkable advantages in the clinical practice. Researchers have attempted to use deep learning methods to detect brain diseases from CT images. Methods often used to detect diseases choose images with visible lesions from full-slice brain CT scans, which need to be labelled by doctors. This is an inaccurate method because doctors detect brain disease from a full sequence scan of CT images and one patient may have multiple concurrent conditions in practice. The method cannot take into account the dependencies between the slices and the causal relationships among various brain diseases. Moreover, labelling images slice by slice spends much time and expense. Detecting multiple diseases from full slice brain CT images is, therefore, an important research subject with practical implications. RESULTS: In this paper, we propose a model called the slice dependencies learning model (SDLM). It learns image features from a series of variable length brain CT images and slice dependencies between different slices in a set of images to predict abnormalities. The model is necessary to only label the disease reflected in the full-slice brain scan. We use the CQ500 dataset to evaluate our proposed model, which contains 1194 full sets of CT scans from a total of 491 subjects. Each set of data from one subject contains scans with one to eight different slice thicknesses and various diseases that are captured in a range of 30 to 396 slices in a set. The evaluation results present that the precision is 67.57%, the recall is 61.04%, the F1 score is 0.6412, and the areas under the receiver operating characteristic curves (AUCs) is 0.8934. CONCLUSION: The proposed model is a new architecture that uses a full-slice brain CT scan for multi-label classification, unlike the traditional methods which only classify the brain images at the slice level. It has great potential for application to multi-label detection problems, especially with regard to the brain CT images. BioMed Central 2020-11-18 /pmc/articles/PMC7672970/ /pubmed/33203366 http://dx.doi.org/10.1186/s12859-020-3503-0 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Li, Jianqiang
Fu, Guanghui
Chen, Yueda
Li, Pengzhi
Liu, Bo
Pei, Yan
Feng, Hui
A multi-label classification model for full slice brain computerised tomography image
title A multi-label classification model for full slice brain computerised tomography image
title_full A multi-label classification model for full slice brain computerised tomography image
title_fullStr A multi-label classification model for full slice brain computerised tomography image
title_full_unstemmed A multi-label classification model for full slice brain computerised tomography image
title_short A multi-label classification model for full slice brain computerised tomography image
title_sort multi-label classification model for full slice brain computerised tomography image
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672970/
https://www.ncbi.nlm.nih.gov/pubmed/33203366
http://dx.doi.org/10.1186/s12859-020-3503-0
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