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Cohort profile: why do people keep hurting their back?

OBJECTIVE: Low back pain (LBP) is one of the most disabling and costly conditions worldwide. It remains unclear why many individuals experience persistent and recurrent symptoms after an acute episode whereas others do not. A longitudinal cohort study was established to address this problem. We aime...

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Autores principales: Klyne, David M., van den Hoorn, Wolbert, Barbe, Mary F., Cholewicki, Jacek, M. Hall, Leanne, Khan, Asaduzzaman, Meroni, Roberto, Moseley, G. Lorimer, Nicholas, Michael, O’Sullivan, Lee, Park, Rachel, Russell, Glen, Sterling, Michele, Hodges, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672992/
https://www.ncbi.nlm.nih.gov/pubmed/33203448
http://dx.doi.org/10.1186/s13104-020-05356-z
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author Klyne, David M.
van den Hoorn, Wolbert
Barbe, Mary F.
Cholewicki, Jacek
M. Hall, Leanne
Khan, Asaduzzaman
Meroni, Roberto
Moseley, G. Lorimer
Nicholas, Michael
O’Sullivan, Lee
Park, Rachel
Russell, Glen
Sterling, Michele
Hodges, Paul W.
author_facet Klyne, David M.
van den Hoorn, Wolbert
Barbe, Mary F.
Cholewicki, Jacek
M. Hall, Leanne
Khan, Asaduzzaman
Meroni, Roberto
Moseley, G. Lorimer
Nicholas, Michael
O’Sullivan, Lee
Park, Rachel
Russell, Glen
Sterling, Michele
Hodges, Paul W.
author_sort Klyne, David M.
collection PubMed
description OBJECTIVE: Low back pain (LBP) is one of the most disabling and costly conditions worldwide. It remains unclear why many individuals experience persistent and recurrent symptoms after an acute episode whereas others do not. A longitudinal cohort study was established to address this problem. We aimed to; (1) evaluate whether promising and potentially modifiable biological, psychological, social and behavioural factors, along with their possible interactions, predict LBP outcome after an acute episode; (2) compare these factors between individuals with and without acute LBP; and (3) evaluate the time-course of changes in these factors from LBP onset. This paper outlines the methodology and compares baseline characteristics between acute LBP and control, and LBP participants with and without follow-up. RESULTS: 133 individuals with acute LBP and 74 pain-free individuals participated. Bio-psycho-social and behavioural measures were collected at baseline and 3-monthly for 12 months (LBP) or 3 months (control). Pain and disability were recorded fortnightly. Baseline characteristics were mostly similar between those who did and did not return for follow-up. Initial analyses of this cohort have revealed important insights into the pathways involved in acute-to-chronic LBP. These and future findings will provide new targets for treatment and prevention of persistent and recurrent LBP.
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spelling pubmed-76729922020-11-20 Cohort profile: why do people keep hurting their back? Klyne, David M. van den Hoorn, Wolbert Barbe, Mary F. Cholewicki, Jacek M. Hall, Leanne Khan, Asaduzzaman Meroni, Roberto Moseley, G. Lorimer Nicholas, Michael O’Sullivan, Lee Park, Rachel Russell, Glen Sterling, Michele Hodges, Paul W. BMC Res Notes Research Note OBJECTIVE: Low back pain (LBP) is one of the most disabling and costly conditions worldwide. It remains unclear why many individuals experience persistent and recurrent symptoms after an acute episode whereas others do not. A longitudinal cohort study was established to address this problem. We aimed to; (1) evaluate whether promising and potentially modifiable biological, psychological, social and behavioural factors, along with their possible interactions, predict LBP outcome after an acute episode; (2) compare these factors between individuals with and without acute LBP; and (3) evaluate the time-course of changes in these factors from LBP onset. This paper outlines the methodology and compares baseline characteristics between acute LBP and control, and LBP participants with and without follow-up. RESULTS: 133 individuals with acute LBP and 74 pain-free individuals participated. Bio-psycho-social and behavioural measures were collected at baseline and 3-monthly for 12 months (LBP) or 3 months (control). Pain and disability were recorded fortnightly. Baseline characteristics were mostly similar between those who did and did not return for follow-up. Initial analyses of this cohort have revealed important insights into the pathways involved in acute-to-chronic LBP. These and future findings will provide new targets for treatment and prevention of persistent and recurrent LBP. BioMed Central 2020-11-17 /pmc/articles/PMC7672992/ /pubmed/33203448 http://dx.doi.org/10.1186/s13104-020-05356-z Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Note
Klyne, David M.
van den Hoorn, Wolbert
Barbe, Mary F.
Cholewicki, Jacek
M. Hall, Leanne
Khan, Asaduzzaman
Meroni, Roberto
Moseley, G. Lorimer
Nicholas, Michael
O’Sullivan, Lee
Park, Rachel
Russell, Glen
Sterling, Michele
Hodges, Paul W.
Cohort profile: why do people keep hurting their back?
title Cohort profile: why do people keep hurting their back?
title_full Cohort profile: why do people keep hurting their back?
title_fullStr Cohort profile: why do people keep hurting their back?
title_full_unstemmed Cohort profile: why do people keep hurting their back?
title_short Cohort profile: why do people keep hurting their back?
title_sort cohort profile: why do people keep hurting their back?
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7672992/
https://www.ncbi.nlm.nih.gov/pubmed/33203448
http://dx.doi.org/10.1186/s13104-020-05356-z
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