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Comparative analysis of adeno-associated virus serotypes for gene transfer in organotypic heart slices
BACKGROUND: Vectors derived from adeno-associated viruses (AAVs) are widely used for gene transfer both in vitro and in vivo and have gained increasing interest as shuttle systems to deliver therapeutic genes to the heart. However, there is little information on their tissue penetration and cytotoxi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673099/ https://www.ncbi.nlm.nih.gov/pubmed/33208161 http://dx.doi.org/10.1186/s12967-020-02605-4 |