Comparative analysis of adeno-associated virus serotypes for gene transfer in organotypic heart slices

BACKGROUND: Vectors derived from adeno-associated viruses (AAVs) are widely used for gene transfer both in vitro and in vivo and have gained increasing interest as shuttle systems to deliver therapeutic genes to the heart. However, there is little information on their tissue penetration and cytotoxi...

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Detalles Bibliográficos
Autores principales: Liu, Zihou, Klose, Kristin, Neuber, Sebastian, Jiang, Meng, Gossen, Manfred, Stamm, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673099/
https://www.ncbi.nlm.nih.gov/pubmed/33208161
http://dx.doi.org/10.1186/s12967-020-02605-4

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