Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells

HIV broadly neutralizing antibodies (bnAbs) can suppress viremia and protect against HIV infection. However, their elicitation is made difficult by low frequencies of appropriate precursor B cell receptors and the complex maturation pathways required to generate bnAbs from these precursors. Antibody...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Deli, Tran, Jenny Tuyet, Olson, Alex, Vollbrecht, Thomas, Tenuta, Mary, Guryleva, Mariia V., Fuller, Roberta P., Schiffner, Torben, Abadejos, Justin R., Couvrette, Lauren, Blane, Tanya R., Saye, Karen, Li, Wenjuan, Landais, Elise, Gonzalez-Martin, Alicia, Schief, William, Murrell, Ben, Burton, Dennis R., Nemazee, David, Voss, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673113/
https://www.ncbi.nlm.nih.gov/pubmed/33203876
http://dx.doi.org/10.1038/s41467-020-19650-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673113/
https://www.ncbi.nlm.nih.gov/pubmed/33203876
http://dx.doi.org/10.1038/s41467-020-19650-8

Ejemplares similares