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Pogz deficiency leads to transcription dysregulation and impaired cerebellar activity underlying autism-like behavior in mice

Several genes implicated in autism spectrum disorder (ASD) are chromatin regulators, including POGZ. The cellular and molecular mechanisms leading to ASD impaired social and cognitive behavior are unclear. Animal models are crucial for studying the effects of mutations on brain function and behavior...

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Detalles Bibliográficos
Autores principales:	Suliman-Lavie, Reut, Title, Ben, Cohen, Yahel, Hamada, Nanako, Tal, Maayan, Tal, Nitzan, Monderer-Rothkoff, Galya, Gudmundsdottir, Bjorg, Gudmundsson, Kristbjorn O., Keller, Jonathan R., Huang, Guo-Jen, Nagata, Koh-ichi, Yarom, Yosef, Shifman, Sagiv
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673123/ https://www.ncbi.nlm.nih.gov/pubmed/33203851 http://dx.doi.org/10.1038/s41467-020-19577-0

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