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High-performance low field MRI enables visualization of persistent pulmonary damage after COVID-19

The outbreak of coronavirus disease 2019 (COVID-19) with the origin of the spread assumed to be located in Wuhan, China, began in December 2019, and is continuing until now. With the COVID-19 pandemic showing a progressive spread throughout the countries of the world, there is emerging interest for...

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Autores principales: Heiss, Rafael, Grodzki, David M., Horger, Wilhelm, Uder, Michael, Nagel, Armin M., Bickelhaupt, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673210/
https://www.ncbi.nlm.nih.gov/pubmed/33220447
http://dx.doi.org/10.1016/j.mri.2020.11.004
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author Heiss, Rafael
Grodzki, David M.
Horger, Wilhelm
Uder, Michael
Nagel, Armin M.
Bickelhaupt, Sebastian
author_facet Heiss, Rafael
Grodzki, David M.
Horger, Wilhelm
Uder, Michael
Nagel, Armin M.
Bickelhaupt, Sebastian
author_sort Heiss, Rafael
collection PubMed
description The outbreak of coronavirus disease 2019 (COVID-19) with the origin of the spread assumed to be located in Wuhan, China, began in December 2019, and is continuing until now. With the COVID-19 pandemic showing a progressive spread throughout the countries of the world, there is emerging interest for the potential long-term consequences of suffering from a COVID-19 pneumonia. Imaging plays a central role in the diagnosis and management of COVID-19 pneumonia, with chest X-ray examinations and computed tomography (CT) being undoubtedly the modalities most widely used, allowing for a fast and sensitive detection of infiltration patterns associated with COVID-19 pneumonia. For a better understanding of underlying pathomechanisms of pulmonary damage, longitudinal imaging series are warranted, for which CT is of limited usability due to repeated exposure of X-rays. Recent advances in MRI suggested that high-performance low-field MRI might represent a valuable method for pulmonary imaging without the need of radiation exposure. However, so far, low-field MRI has not been applied to study pulmonary damage after COVID-19 pneumonia. We present a case report of a patient who suffered from COVID-19 pneumonia using 0.55 T MRI for follow-up examinations three months after initial infection. Low-field MRI enables a precise visualization of persistent pulmonary changes including ground-glass opacities, which are consistent with CT performed on the same day. Low-field MRI seems to be feasible in the detection of pulmonary involvement in patients with COVID-19 pneumonia and may have the potential for repetitive lung examinations in monitoring the reconvalescence after pulmonary infections.
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spelling pubmed-76732102020-11-19 High-performance low field MRI enables visualization of persistent pulmonary damage after COVID-19 Heiss, Rafael Grodzki, David M. Horger, Wilhelm Uder, Michael Nagel, Armin M. Bickelhaupt, Sebastian Magn Reson Imaging Case Report The outbreak of coronavirus disease 2019 (COVID-19) with the origin of the spread assumed to be located in Wuhan, China, began in December 2019, and is continuing until now. With the COVID-19 pandemic showing a progressive spread throughout the countries of the world, there is emerging interest for the potential long-term consequences of suffering from a COVID-19 pneumonia. Imaging plays a central role in the diagnosis and management of COVID-19 pneumonia, with chest X-ray examinations and computed tomography (CT) being undoubtedly the modalities most widely used, allowing for a fast and sensitive detection of infiltration patterns associated with COVID-19 pneumonia. For a better understanding of underlying pathomechanisms of pulmonary damage, longitudinal imaging series are warranted, for which CT is of limited usability due to repeated exposure of X-rays. Recent advances in MRI suggested that high-performance low-field MRI might represent a valuable method for pulmonary imaging without the need of radiation exposure. However, so far, low-field MRI has not been applied to study pulmonary damage after COVID-19 pneumonia. We present a case report of a patient who suffered from COVID-19 pneumonia using 0.55 T MRI for follow-up examinations three months after initial infection. Low-field MRI enables a precise visualization of persistent pulmonary changes including ground-glass opacities, which are consistent with CT performed on the same day. Low-field MRI seems to be feasible in the detection of pulmonary involvement in patients with COVID-19 pneumonia and may have the potential for repetitive lung examinations in monitoring the reconvalescence after pulmonary infections. Elsevier Inc. 2021-02 2020-11-18 /pmc/articles/PMC7673210/ /pubmed/33220447 http://dx.doi.org/10.1016/j.mri.2020.11.004 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Heiss, Rafael
Grodzki, David M.
Horger, Wilhelm
Uder, Michael
Nagel, Armin M.
Bickelhaupt, Sebastian
High-performance low field MRI enables visualization of persistent pulmonary damage after COVID-19
title High-performance low field MRI enables visualization of persistent pulmonary damage after COVID-19
title_full High-performance low field MRI enables visualization of persistent pulmonary damage after COVID-19
title_fullStr High-performance low field MRI enables visualization of persistent pulmonary damage after COVID-19
title_full_unstemmed High-performance low field MRI enables visualization of persistent pulmonary damage after COVID-19
title_short High-performance low field MRI enables visualization of persistent pulmonary damage after COVID-19
title_sort high-performance low field mri enables visualization of persistent pulmonary damage after covid-19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673210/
https://www.ncbi.nlm.nih.gov/pubmed/33220447
http://dx.doi.org/10.1016/j.mri.2020.11.004
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