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Duchenne muscular dystrophy (DMD) cardiomyocyte-secreted exosomes promote the pathogenesis of DMD-associated cardiomyopathy

Cardiomyopathy is a leading cause of early mortality in Duchenne muscular dystrophy (DMD). There is a need to gain a better understanding of the molecular pathogenesis for the development effective therapies. Exosomes (exo) are secreted vesicles and exert effects via their RNA, lipid and protein car...

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Detalles Bibliográficos
Autores principales: Gartz, Melanie, Lin, Chien-Wei, Sussman, Mark A., Lawlor, Michael W., Strande, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673361/
https://www.ncbi.nlm.nih.gov/pubmed/33188007
http://dx.doi.org/10.1242/dmm.045559