Cargando…
STAT3 decoy oligonucleotide-carrying microbubbles with pulsed ultrasound for enhanced therapeutic effect in head and neck tumors
Signal transducer and activator of transcription-3 (STAT3) is an oncogenic transcription factor implicated in carcinogenesis, tumor progression, and drug resistance in head and neck squamous cell carcinoma (HNSCC). A decoy oligonucleotide targeting STAT3 offers a promising anti-tumor strategy, but a...
Autores principales: | Ramasamy, Thiruganesh, Chen, Xucai, Qin, Bin, Johnson, Daniel E., Grandis, Jennifer R., Villanueva, Flordeliza S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673576/ https://www.ncbi.nlm.nih.gov/pubmed/33206698 http://dx.doi.org/10.1371/journal.pone.0242264 |
Ejemplares similares
-
Ultrasound Targeted Microbubble Destruction-Mediated Delivery of a Transcription Factor Decoy Inhibits STAT3 Signaling and Tumor Growth
por: Kopechek, Jonathan A., et al.
Publicado: (2015) -
Cardiac Gene Expression Knockdown Using Small Inhibitory RNA-Loaded Microbubbles and Ultrasound
por: Kopechek, Jonathan A., et al.
Publicado: (2016) -
Focal areas of increased lipid concentration on the coating of microbubbles during short tone-burst ultrasound insonification
por: Kooiman, Klazina, et al.
Publicado: (2017) -
Ultrasound and Microbubble-targeted Delivery of a microRNA Inhibitor to the Heart Suppresses Cardiac Hypertrophy and Preserves Cardiac Function
por: Kopechek, Jonathan A., et al.
Publicado: (2019) -
Effect of STAT3 decoy oligodeoxynucleotides mediated by ultrasound-targeted microbubbles combined with ultrasound on the growth of squamous cell carcinoma of the esophagus
por: Zhang, Yan, et al.
Publicado: (2019)