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Metabolic determinants of cellular fitness dependent on mitochondrial reactive oxygen species

Mitochondria-derived reactive oxygen species (mROS) are required for the survival, proliferation, and metastasis of cancer cells. The mechanism by which mitochondrial metabolism regulates mROS levels to support cancer cells is not fully understood. To address this, we conducted a metabolism-focused...

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Detalles Bibliográficos
Autores principales:	Kong, Hyewon, Reczek, Colleen R., McElroy, Gregory S., Steinert, Elizabeth M., Wang, Tim, Sabatini, David M., Chandel, Navdeep S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673681/ https://www.ncbi.nlm.nih.gov/pubmed/33148642 http://dx.doi.org/10.1126/sciadv.abb7272

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