Cargando…

Spider silk self-assembly via modular liquid-liquid phase separation and nanofibrillation

Spider silk fiber rapidly assembles from spidroin protein in soluble state via an incompletely understood mechanism. Here, we present an integrated model for silk formation that incorporates the effects of multiple chemical and physical gradients on the different spidroin functional domains. Central...

Descripción completa

Detalles Bibliográficos
Autores principales:	Malay, Ali D., Suzuki, Takehiro, Katashima, Takuya, Kono, Nobuaki, Arakawa, Kazuharu, Numata, Keiji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673682/ https://www.ncbi.nlm.nih.gov/pubmed/33148640 http://dx.doi.org/10.1126/sciadv.abb6030

Ejemplares similares

Analysis of repetitive amino acid motifs reveals the essential features of spider dragline silk proteins
por: Malay, Ali D., et al.
Publicado: (2017)

Darwin's bark spider shares a spidroin repertoire with Caerostris extrusa but achieves extraordinary silk toughness through gene expression
por: Kono, Nobuaki, et al.
Publicado: (2021)

The balance of crystalline and amorphous regions in the fibroin structure underpins the tensile strength of bagworm silk
por: Kono, Nobuaki, et al.
Publicado: (2021)

Complexity of Spider Dragline Silk
por: Malay, Ali D., et al.
Publicado: (2022)

Xanthurenic Acid Is the Main Pigment of Trichonephila clavata Gold Dragline Silk
por: Fujiwara, Masayuki, et al.
Publicado: (2021)

Protein secondary structure in spider silk nanofibrils
por: Wang, Qijue, et al.
Publicado: (2022)

Unusual pK(a) Values Mediate the Self-Assembly of Spider Dragline Silk Proteins
por: Oktaviani, Nur Alia, et al.
Publicado: (2023)

Liquid–Liquid Phase Separation and Assembly of Silk-like Proteins is Dependent on the Polymer Length
por: Lemetti, Laura, et al.
Publicado: (2022)

Liquid–Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain
por: Leppert, Axel, et al.
Publicado: (2023)

Spidroin profiling of cribellate spiders provides insight into the evolution of spider prey capture strategies
por: Kono, Nobuaki, et al.
Publicado: (2020)

1000 spider silkomes: Linking sequences to silk physical properties
por: Arakawa, Kazuharu, et al.
Publicado: (2022)

Biomimetic Nanofibrillation in Two-Component Biopolymer Blends with Structural Analogs to Spider Silk
por: Xie, Lan, et al.
Publicado: (2016)

Molecular mechanisms of the high performance of spider silks revealed through multi-omics analysis
por: Watanabe, Yasuha, et al.
Publicado: (2023)

A marine photosynthetic microbial cell factory as a platform for spider silk production
por: Foong, Choon Pin, et al.
Publicado: (2020)

Conformation and dynamics of soluble repetitive domain elucidates the initial β-sheet formation of spider silk
por: Oktaviani, Nur Alia, et al.
Publicado: (2018)

The bagworm genome reveals a unique fibroin gene that provides high tensile strength
por: Kono, Nobuaki, et al.
Publicado: (2019)

Silk Assembly against Hydrophobic Surfaces—Modeling and Imaging of Formation of Nanofibrils
por: De Oliveira, Danilo Hirabae, et al.
Publicado: (2023)

eRP arrangement: a strategy for assembled genomic contig rearrangement based on replication profiling in bacteria
por: Kono, Nobuaki, et al.
Publicado: (2017)

Self-assembly coupled to liquid-liquid phase separation
por: Hagan, Michael F., et al.
Publicado: (2023)

Spider dragline silk composite films doped with linear and telechelic polyalanine: Effect of polyalanine on the structure and mechanical properties
por: Tsuchiya, Kousuke, et al.
Publicado: (2018)

Liquid–liquid phase separation drives herpesvirus assembly in the cytoplasm
por: Chung, Woo-Chang, et al.
Publicado: (2022)

Controllable Production of Natural Silk Nanofibrils for Reinforcing Silk-Based Orthopedic Screws
por: Yan, Shuqin, et al.
Publicado: (2023)

Liquid–liquid phase separation mediates the formation of herpesvirus assembly compartments
por: Zhou, Sheng, et al.
Publicado: (2022)

Spider Silk-CBD-Cellulose Nanocrystal Composites: Mechanism of Assembly
por: Meirovitch, Sigal, et al.
Publicado: (2016)

Preparation of Highly Crystalline Silk Nanofibrils and Their Use in the Improvement of the Mechanical Properties of Silk Films
por: Lee, Ji Hye, et al.
Publicado: (2022)

Automated Robotic Liquid Handling Assembly of Modular DNA Devices
por: Ortiz, Luis, et al.
Publicado: (2017)

Spider wrapping silk fibre architecture arising from its modular soluble protein precursor
por: Tremblay, Marie-Laurence, et al.
Publicado: (2015)

Effect of nuclear import receptors on liquid–liquid phase separation
por: Yoshizawa, Takuya, et al.
Publicado: (2020)

Spider silk gut: Development and characterization of a novel strong spider silk fiber
por: Jiang, Ping, et al.
Publicado: (2014)

Orb-weaving spider Araneus ventricosus genome elucidates the spidroin gene catalogue
por: Kono, Nobuaki, et al.
Publicado: (2019)

Spider silks: recombinant synthesis, assembly, spinning, and engineering of synthetic proteins
por: Scheibel, Thomas
Publicado: (2004)

Two-step self-assembly of a spider silk molecular clamp
por: Rat, Charlotte, et al.
Publicado: (2018)

How Spiders Spin Silk
por: Meadows, Robin
Publicado: (2014)

Silk Spinning in Silkworms and Spiders
por: Andersson, Marlene, et al.
Publicado: (2016)

The myth of antibiotic spider silk
por: Fruergaard, Simon, et al.
Publicado: (2021)

Shifts in morphology, gene expression, and selection underlie web loss in Hawaiian Tetragnatha spiders
por: Berger, Cory A., et al.
Publicado: (2021)

Silk nanofibrils-MOF composite membranes for pollutant removal from water
por: Zhao, Xiaowen, et al.
Publicado: (2023)

Silk Nanofibril-Palygorskite Composite Membranes for Efficient Removal of Anionic Dyes
por: Wang, Xu-rui, et al.
Publicado: (2023)

Presence of β-Turn Structure in Recombinant Spider Silk Dissolved in Formic Acid Revealed with NMR
por: Suzuki, Yu, et al.
Publicado: (2022)

Liquid–liquid phase separation in autophagy
por: Noda, Nobuo N., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_li68sp7us7i15bf06fqoboh10j