Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice

Hepatitis C virus (HCV) has no animal reservoir, infecting only humans. To investigate species barrier determinants limiting infection of rodents, murine liver complementary DNA library screening was performed, identifying transmembrane proteins Cd302 and Cr1l as potent restrictors of HCV propagatio...

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Detalles Bibliográficos
Autores principales: Brown, Richard J. P., Tegtmeyer, Birthe, Sheldon, Julie, Khera, Tanvi, Anggakusuma, Todt, Daniel, Vieyres, Gabrielle, Weller, Romy, Joecks, Sebastian, Zhang, Yudi, Sake, Svenja, Bankwitz, Dorothea, Welsch, Kathrin, Ginkel, Corinne, Engelmann, Michael, Gerold, Gisa, Steinmann, Eike, Yuan, Qinggong, Ott, Michael, Vondran, Florian W. R., Krey, Thomas, Ströh, Luisa J., Miskey, Csaba, Ivics, Zoltán, Herder, Vanessa, Baumgärtner, Wolfgang, Lauber, Chris, Seifert, Michael, Tarr, Alexander W., McClure, C. Patrick, Randall, Glenn, Baktash, Yasmine, Ploss, Alexander, Thi, Viet Loan Dao, Michailidis, Eleftherios, Saeed, Mohsan, Verhoye, Lieven, Meuleman, Philip, Goedecke, Natascha, Wirth, Dagmar, Rice, Charles M., Pietschmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673688/
https://www.ncbi.nlm.nih.gov/pubmed/33148654
http://dx.doi.org/10.1126/sciadv.abd3233

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