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Genome-scale phylogeny and contrasting modes of genome evolution in the fungal phylum Ascomycota
Ascomycota, the largest and most well-studied phylum of fungi, contains three subphyla: Saccharomycotina (budding yeasts), Pezizomycotina (filamentous fungi), and Taphrinomycotina (fission yeasts). Despite its importance, we lack a comprehensive genome-scale phylogeny or understanding of the similar...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American Association for the Advancement of Science
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673691/ https://www.ncbi.nlm.nih.gov/pubmed/33148650 http://dx.doi.org/10.1126/sciadv.abd0079 |
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author | Shen, Xing-Xing Steenwyk, Jacob L. LaBella, Abigail L. Opulente, Dana A. Zhou, Xiaofan Kominek, Jacek Li, Yuanning Groenewald, Marizeth Hittinger, Chris T. Rokas, Antonis |
author_facet | Shen, Xing-Xing Steenwyk, Jacob L. LaBella, Abigail L. Opulente, Dana A. Zhou, Xiaofan Kominek, Jacek Li, Yuanning Groenewald, Marizeth Hittinger, Chris T. Rokas, Antonis |
author_sort | Shen, Xing-Xing |
collection | PubMed |
description | Ascomycota, the largest and most well-studied phylum of fungi, contains three subphyla: Saccharomycotina (budding yeasts), Pezizomycotina (filamentous fungi), and Taphrinomycotina (fission yeasts). Despite its importance, we lack a comprehensive genome-scale phylogeny or understanding of the similarities and differences in the mode of genome evolution within this phylum. By examining 1107 genomes from Saccharomycotina (332), Pezizomycotina (761), and Taphrinomycotina (14) species, we inferred a robust genome-wide phylogeny that resolves several contentious relationships and estimated that the Ascomycota last common ancestor likely originated in the Ediacaran period. Comparisons of genomic properties revealed that Saccharomycotina and Pezizomycotina differ greatly in their genome properties and enabled inference of the direction of evolutionary change. The Saccharomycotina typically have smaller genomes, lower guanine-cytosine contents, lower numbers of genes, and higher rates of molecular sequence evolution compared with Pezizomycotina. These results provide a robust evolutionary framework for understanding the diversity and ecological lifestyles of the largest fungal phylum. |
format | Online Article Text |
id | pubmed-7673691 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | American Association for the Advancement of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-76736912020-11-24 Genome-scale phylogeny and contrasting modes of genome evolution in the fungal phylum Ascomycota Shen, Xing-Xing Steenwyk, Jacob L. LaBella, Abigail L. Opulente, Dana A. Zhou, Xiaofan Kominek, Jacek Li, Yuanning Groenewald, Marizeth Hittinger, Chris T. Rokas, Antonis Sci Adv Research Articles Ascomycota, the largest and most well-studied phylum of fungi, contains three subphyla: Saccharomycotina (budding yeasts), Pezizomycotina (filamentous fungi), and Taphrinomycotina (fission yeasts). Despite its importance, we lack a comprehensive genome-scale phylogeny or understanding of the similarities and differences in the mode of genome evolution within this phylum. By examining 1107 genomes from Saccharomycotina (332), Pezizomycotina (761), and Taphrinomycotina (14) species, we inferred a robust genome-wide phylogeny that resolves several contentious relationships and estimated that the Ascomycota last common ancestor likely originated in the Ediacaran period. Comparisons of genomic properties revealed that Saccharomycotina and Pezizomycotina differ greatly in their genome properties and enabled inference of the direction of evolutionary change. The Saccharomycotina typically have smaller genomes, lower guanine-cytosine contents, lower numbers of genes, and higher rates of molecular sequence evolution compared with Pezizomycotina. These results provide a robust evolutionary framework for understanding the diversity and ecological lifestyles of the largest fungal phylum. American Association for the Advancement of Science 2020-11-04 /pmc/articles/PMC7673691/ /pubmed/33148650 http://dx.doi.org/10.1126/sciadv.abd0079 Text en Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (https://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited. |
spellingShingle | Research Articles Shen, Xing-Xing Steenwyk, Jacob L. LaBella, Abigail L. Opulente, Dana A. Zhou, Xiaofan Kominek, Jacek Li, Yuanning Groenewald, Marizeth Hittinger, Chris T. Rokas, Antonis Genome-scale phylogeny and contrasting modes of genome evolution in the fungal phylum Ascomycota |
title | Genome-scale phylogeny and contrasting modes of genome evolution in the fungal phylum Ascomycota |
title_full | Genome-scale phylogeny and contrasting modes of genome evolution in the fungal phylum Ascomycota |
title_fullStr | Genome-scale phylogeny and contrasting modes of genome evolution in the fungal phylum Ascomycota |
title_full_unstemmed | Genome-scale phylogeny and contrasting modes of genome evolution in the fungal phylum Ascomycota |
title_short | Genome-scale phylogeny and contrasting modes of genome evolution in the fungal phylum Ascomycota |
title_sort | genome-scale phylogeny and contrasting modes of genome evolution in the fungal phylum ascomycota |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673691/ https://www.ncbi.nlm.nih.gov/pubmed/33148650 http://dx.doi.org/10.1126/sciadv.abd0079 |
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