Transcriptional priming as a conserved mechanism of lineage diversification in the developing mouse and human neocortex

How the rich variety of neurons in the nervous system arises from neural stem cells is not well understood. Using single-cell RNA-sequencing and in vivo confirmation, we uncover previously unrecognized neural stem and progenitor cell diversity within the fetal mouse and human neocortex, including mu...

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Detalles Bibliográficos
Autores principales: Li, Zhen, Tyler, William A., Zeldich, Ella, Santpere Baró, Gabriel, Okamoto, Mayumi, Gao, Tianliuyun, Li, Mingfeng, Sestan, Nenad, Haydar, Tarik F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673705/
https://www.ncbi.nlm.nih.gov/pubmed/33158872
http://dx.doi.org/10.1126/sciadv.abd2068

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