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The 3.2-Å resolution structure of human mTORC2

The protein kinase mammalian target of rapamycin (mTOR) is the central regulator of cell growth. Aberrant mTOR signaling is linked to cancer, diabetes, and neurological disorders. mTOR exerts its functions in two distinct multiprotein complexes, mTORC1 and mTORC2. Here, we report a 3.2-Å resolution...

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Detalles Bibliográficos
Autores principales:	Scaiola, Alain, Mangia, Francesca, Imseng, Stefan, Boehringer, Daniel, Berneiser, Karolin, Shimobayashi, Mitsugu, Stuttfeld, Edward, Hall, Michael N., Ban, Nenad, Maier, Timm
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673708/ https://www.ncbi.nlm.nih.gov/pubmed/33158864 http://dx.doi.org/10.1126/sciadv.abc1251

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