COVID-19 in Elderly Adults: Clinical Features, Molecular Mechanisms, and Proposed Strategies

Coronavirus disease 2019 (COVID-19) is causing problems worldwide. Most people are susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but elderly populations are more susceptible. Elevated susceptibility and death rates in elderly COVID-19 patients, especially those with ag...

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Detalles Bibliográficos
Autores principales: Yang, Ya, Zhao, Yalei, Zhang, Fen, Zhang, Lingjian, Li, Lanjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673861/
https://www.ncbi.nlm.nih.gov/pubmed/33269102
http://dx.doi.org/10.14336/AD.2020.0903
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author Yang, Ya
Zhao, Yalei
Zhang, Fen
Zhang, Lingjian
Li, Lanjuan
author_facet Yang, Ya
Zhao, Yalei
Zhang, Fen
Zhang, Lingjian
Li, Lanjuan
author_sort Yang, Ya
collection PubMed
description Coronavirus disease 2019 (COVID-19) is causing problems worldwide. Most people are susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but elderly populations are more susceptible. Elevated susceptibility and death rates in elderly COVID-19 patients, especially those with age-related complications, are challenges for pandemic prevention and control. In this paper, we review the clinical features of elderly patients with COVID-19 and explore the related molecular mechanisms that are essential for the exploration of preventive and therapeutic strategies in the current pandemic. Furthermore, we analyze the feasibility of currently recommended potential novel methods against COVID-19 among elderly populations.
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spelling pubmed-76738612020-12-01 COVID-19 in Elderly Adults: Clinical Features, Molecular Mechanisms, and Proposed Strategies Yang, Ya Zhao, Yalei Zhang, Fen Zhang, Lingjian Li, Lanjuan Aging Dis Review Article Coronavirus disease 2019 (COVID-19) is causing problems worldwide. Most people are susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but elderly populations are more susceptible. Elevated susceptibility and death rates in elderly COVID-19 patients, especially those with age-related complications, are challenges for pandemic prevention and control. In this paper, we review the clinical features of elderly patients with COVID-19 and explore the related molecular mechanisms that are essential for the exploration of preventive and therapeutic strategies in the current pandemic. Furthermore, we analyze the feasibility of currently recommended potential novel methods against COVID-19 among elderly populations. JKL International LLC 2020-12-01 /pmc/articles/PMC7673861/ /pubmed/33269102 http://dx.doi.org/10.14336/AD.2020.0903 Text en copyright: © 2020 Yang et al. http://creativecommons.org/licenses/by/2.0/ this is an open access article distributed under the terms of the creative commons attribution license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Review Article
Yang, Ya
Zhao, Yalei
Zhang, Fen
Zhang, Lingjian
Li, Lanjuan
COVID-19 in Elderly Adults: Clinical Features, Molecular Mechanisms, and Proposed Strategies
title COVID-19 in Elderly Adults: Clinical Features, Molecular Mechanisms, and Proposed Strategies
title_full COVID-19 in Elderly Adults: Clinical Features, Molecular Mechanisms, and Proposed Strategies
title_fullStr COVID-19 in Elderly Adults: Clinical Features, Molecular Mechanisms, and Proposed Strategies
title_full_unstemmed COVID-19 in Elderly Adults: Clinical Features, Molecular Mechanisms, and Proposed Strategies
title_short COVID-19 in Elderly Adults: Clinical Features, Molecular Mechanisms, and Proposed Strategies
title_sort covid-19 in elderly adults: clinical features, molecular mechanisms, and proposed strategies
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7673861/
https://www.ncbi.nlm.nih.gov/pubmed/33269102
http://dx.doi.org/10.14336/AD.2020.0903
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