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Protein-ligand binding interactions of imidazolium salts with SARS CoV-2
The disease called severe acute respiratory syndrome (SARS) is a lifestyle intimidating viral contamination affected by a positive, single stranded novel RNA virus (COVID-2019) from the enveloped coronaviruse family. The COVID-2019 virus has affected many people, scattering promptly, and researchers...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674018/ https://www.ncbi.nlm.nih.gov/pubmed/33230487 http://dx.doi.org/10.1016/j.heliyon.2020.e05544 |
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author | Satheesh, Dhurairaj Rajendran, Annamalai Chithra, Kasi |
author_facet | Satheesh, Dhurairaj Rajendran, Annamalai Chithra, Kasi |
author_sort | Satheesh, Dhurairaj |
collection | PubMed |
description | The disease called severe acute respiratory syndrome (SARS) is a lifestyle intimidating viral contamination affected by a positive, single stranded novel RNA virus (COVID-2019) from the enveloped coronaviruse family. The COVID-2019 virus has affected many people, scattering promptly, and researchers are attempting to find out medicines for its effectual cure in all over the globe. Chloroquine (ChQ) and its derivatives, an older drug used for the cure of malaria, is exposed to encompass a perceptible feasibility and commendable well-being in opposition to SARS CoV-2 associated pneumonia clinical trials conducted in China. Later on, a few investigations have been directed to find and present SARS CoV-2 antiviral medications. The aim of this present work deals with the potential binding interactions of some imidazolium salts with Nsp9 (Nonstructural protein 9) RNA binding protein of SARS CoV-2. |
format | Online Article Text |
id | pubmed-7674018 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-76740182020-11-19 Protein-ligand binding interactions of imidazolium salts with SARS CoV-2 Satheesh, Dhurairaj Rajendran, Annamalai Chithra, Kasi Heliyon Research Article The disease called severe acute respiratory syndrome (SARS) is a lifestyle intimidating viral contamination affected by a positive, single stranded novel RNA virus (COVID-2019) from the enveloped coronaviruse family. The COVID-2019 virus has affected many people, scattering promptly, and researchers are attempting to find out medicines for its effectual cure in all over the globe. Chloroquine (ChQ) and its derivatives, an older drug used for the cure of malaria, is exposed to encompass a perceptible feasibility and commendable well-being in opposition to SARS CoV-2 associated pneumonia clinical trials conducted in China. Later on, a few investigations have been directed to find and present SARS CoV-2 antiviral medications. The aim of this present work deals with the potential binding interactions of some imidazolium salts with Nsp9 (Nonstructural protein 9) RNA binding protein of SARS CoV-2. Elsevier 2020-11-19 /pmc/articles/PMC7674018/ /pubmed/33230487 http://dx.doi.org/10.1016/j.heliyon.2020.e05544 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Article Satheesh, Dhurairaj Rajendran, Annamalai Chithra, Kasi Protein-ligand binding interactions of imidazolium salts with SARS CoV-2 |
title | Protein-ligand binding interactions of imidazolium salts with SARS CoV-2 |
title_full | Protein-ligand binding interactions of imidazolium salts with SARS CoV-2 |
title_fullStr | Protein-ligand binding interactions of imidazolium salts with SARS CoV-2 |
title_full_unstemmed | Protein-ligand binding interactions of imidazolium salts with SARS CoV-2 |
title_short | Protein-ligand binding interactions of imidazolium salts with SARS CoV-2 |
title_sort | protein-ligand binding interactions of imidazolium salts with sars cov-2 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674018/ https://www.ncbi.nlm.nih.gov/pubmed/33230487 http://dx.doi.org/10.1016/j.heliyon.2020.e05544 |
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