Cargando…

Interleukin-15 and cancer: some solved and many unsolved questions

Soluble interleukin (IL)-15 exists under two forms: as monomer (sIL-15) or as heterodimeric complex in association with sIL-15Rα (sIL-15/IL-15Rα). Both forms have been successfully tested in experimental tumor murine models and are currently undergoing investigation in phase I/II clinical trials. De...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fiore, Piera Filomena, Di Matteo, Sabina, Tumino, Nicola, Mariotti, Francesca Romana, Pietra, Gabriella, Ottonello, Selene, Negrini, Simone, Bottazzi, Barbara, Moretta, Lorenzo, Mortier, Erwan, Azzarone, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674108/ https://www.ncbi.nlm.nih.gov/pubmed/33203664 http://dx.doi.org/10.1136/jitc-2020-001428

Ejemplares similares

The roles of different forms of IL-15 in human melanoma progression
por: Di Matteo, Sabina, et al.
Publicado: (2023)

Ambulance Problems Solved and Unsolved
Publicado: (1914)

Solving the unsolved rare diseases in Europe
por: Graessner, Holm, et al.
Publicado: (2021)

Wilms’ Tumor Primary Cells Display Potent Immunoregulatory Properties on NK Cells and Macrophages
por: Fiore, Piera Filomena, et al.
Publicado: (2021)

Chagas Disease: Still Many Unsolved Issues
por: Álvarez, José M., et al.
Publicado: (2014)

Solving unsolved rare neurological diseases—a Solve-RD viewpoint
por: Schüle, Rebecca, et al.
Publicado: (2021)

Pediatric Tumors-Mediated Inhibitory Effect on NK Cells: The Case of Neuroblastoma and Wilms’ Tumors
por: Pelosi, Andrea, et al.
Publicado: (2021)

The Higgs Boson: Current Status and Unsolved Questions
por: Gray, Heather
Publicado: (2018)

Unsolved Questions on the Anatomy of the Ventricular Conduction System
por: Oh, Il-Young, et al.
Publicado: (2018)

Fungi in the Marine Environment: Open Questions and Unsolved Problems
por: Amend, Anthony, et al.
Publicado: (2019)

Fondaparinux and bleeding risk in COVID-19: unsolved question
por: Russo, Vincenzo, et al.
Publicado: (2021)

Colchicine treatment in COVID-19: the remaining unsolved question
por: Rojas-Villarraga, Adriana, et al.
Publicado: (2021)

NATO Advanced Research Workshop on Earth Rotation : Solved and Unsolved Problems
por: Cazenave, Anny
Publicado: (1986)

Systematic review on strength training in Parkinson’s disease: an unsolved question
por: Ramazzina, Ileana, et al.
Publicado: (2017)

Cholecystokinin and Panic Disorder: Reflections on the History and Some Unsolved Questions
por: Rehfeld, Jens F.
Publicado: (2021)

To implant or not to implant?: That is the unsolved question concerning heart failure patients with non-LBBB
por: Zarse, M., et al.
Publicado: (2015)

Subclinical and Asymptomatic Atrial Fibrillation: Current Evidence and Unsolved Questions in Clinical Practice
por: Ballatore, Andrea, et al.
Publicado: (2019)

Lymph Nodes Involvement and Lymphadenectomy in Thymic Tumors: Tentative Answers for Unsolved Questions
por: Brascia, Debora, et al.
Publicado: (2021)

Transsphenoidal pituitary surgery by microscopic or endoscopic approach: the still unsolved question of superiority
por: Vellutini, Eduardo de Arnaldo S.
Publicado: (2016)

150th Anniversary of global adenoid investigations: unanswered questions and unsolved problems
por: Zwierz, Aleksander, et al.
Publicado: (2023)

The jigsaw puzzle of our African ancestry: unsolved, or unsolvable?
por: Batini, Chiara, et al.
Publicado: (2011)

Unsolved problems in geometry: unsolved problems in intuitive mathematics
por: Croft, Hallard T, et al.
Publicado: (1991)

MicroRNA analysis of Natural Killer cell-derived exosomes: the microRNA let-7b-5p is enriched in exosomes and participates in their anti-tumor effects against pancreatic cancer cells
por: Di Pace, Anna Laura, et al.
Publicado: (2023)

Degrees of unsolvability
por: Shoenfield, Joseph R
Publicado: (2011)

Computability & Unsolvability
por: Davis, Martin, 1928-
Publicado: (1982)

An Unsolved Mystery
Publicado: (1920)

Helper Innate Lymphoid Cells in Human Tumors: A Double-Edged Sword?
por: Tumino, Nicola, et al.
Publicado: (2020)

Different effects of NK cells and NK-derived soluble factors on cell lines derived from primary or metastatic pancreatic cancers
por: Fiore, Piera Filomena, et al.
Publicado: (2022)

The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy
por: Quatrini, Linda, et al.
Publicado: (2020)

Unsolved Questions in Salvage TIPSS: Practical Modalities for Placement, Alternative Therapeutics, and Long-Term Outcomes
por: Bouzbib, Charlotte, et al.
Publicado: (2019)

Autoantigen Treatment in Type 1 Diabetes: Unsolved Questions on How to Select Autoantigen and Administration Route
por: Ludvigsson, Johnny
Publicado: (2020)

HPV Vaccination in Women with Cervical Intraepithelial Neoplasia Undergoing Excisional Treatment: Insights into Unsolved Questions
por: Henere, Carla, et al.
Publicado: (2022)

Unsolved problems in astrophysics
por: Ostriker, Jeremiah P, et al.
Publicado: (1997)

Solving the puzzle of autoimmunity: critical questions
por: Smilek, Dawn E., et al.
Publicado: (2015)

The tumor microenvironment drives NK cell metabolic dysfunction leading to impaired antitumor activity
por: Tumino, Nicola, et al.
Publicado: (2022)

The unsolved riddle of Ettore Majorana
Publicado: (1998)

Unsolved problems in number theory
por: Guy, Richard K
Publicado: (1981)

Degrees of unsolvability (AM-55)
por: Sacks, Gerald E
Publicado: (1964)

The Unsolved Universe: Challenges for the Future
por: Collective
Publicado: (2002)

Unsolved Problems in Stellar Physics
por: Collective
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_6bv683lebc8aj20q5g681pehig