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Mycobacterial Hsp65 antigen delivered by invasive Lactococcus lactis reduces intestinal inflammation and fibrosis in TNBS-induced chronic colitis model
Intestinal fibrosis associated with Crohn’s disease (CD), which a common and serious complication of inflammatory bowel diseases. In this context, heat shock proteins (HSPs) might serve as an alternative treatment because these antigens play important roles in the regulation of effector T cells. We...
Autores principales: | da Cunha, Vanessa Pecini, Preisser, Tatiane Melo, Santana, Mariana Passos, Machado, Denise Carmona Cara, Pereira, Vanessa Bastos, Miyoshi, Anderson |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674425/ https://www.ncbi.nlm.nih.gov/pubmed/33208841 http://dx.doi.org/10.1038/s41598-020-77276-8 |
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